Viral infection and aging as cofactors for the development of pulmonary fibrosis
PK Naik, BB Moore - Expert review of respiratory medicine, 2010 - Taylor & Francis
… We were successful in modeling a rapid exacerbation of pulmonary fibrosis using MHV-68
infection in mice with already established pulmonary fibrosis. Mice with established FITC-…
infection in mice with already established pulmonary fibrosis. Mice with established FITC-…
Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1
R Eferl, P Hasselblatt, M Rath… - Proceedings of the …, 2008 - National Acad Sciences
… pulmonary fibrosis. These findings indicate that Fra-2 expression is sufficient to cause pulmonary
fibrosis in … considered a contributing pathogenic factor of pulmonary fibrosis in humans. …
fibrosis in … considered a contributing pathogenic factor of pulmonary fibrosis in humans. …
Serial development of pulmonary hypertension in patients with idiopathic pulmonary fibrosis
… Background: Idiopathic pulmonary fibrosis (IPF) is a disease with very high mortality.
Objective: We sought to characterize serial changes in pulmonary artery pressures (PAP) in …
Objective: We sought to characterize serial changes in pulmonary artery pressures (PAP) in …
[HTML][HTML] Challenges for clinical drug development in pulmonary fibrosis
… pulmonary fibrosis that leads to respiratory failure and death. Idiopathic pulmonary fibrosis
(… of progressive fibrosing ILD, and the development of pirfenidone and nintedanib has been a …
(… of progressive fibrosing ILD, and the development of pirfenidone and nintedanib has been a …
[HTML][HTML] Pulmonary fibrosis: pathogenesis, etiology and regulation
MS Wilson, TA Wynn - Mucosal immunology, 2009 - Elsevier
… pulmonary fibrotic conditions, idiopathic pulmonary fibrosis (IPF), is still unclear. This review
examines common mechanisms of pulmonary … most widespread pulmonary fibrotic diseases…
examines common mechanisms of pulmonary … most widespread pulmonary fibrotic diseases…
Idiopathic pulmonary fibrosis: Disease mechanisms and drug development
P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
… The importance of dysregulation of alveolar epithelial cells in the initiation of pulmonary
fibrosis has been strengthened by the recent observation that an IPF-associated mutation in the …
fibrosis has been strengthened by the recent observation that an IPF-associated mutation in the …
[HTML][HTML] Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis
K Kuwano, N Hagimoto, M Kawasaki… - The Journal of …, 1999 - Am Soc Clin Investig
… To investigate the role of Fas-FasL interaction in the development of bleomycin-induced
pulmonary fibrosis, we used hFas-Fc in which the extracellular region of human Fas is fused to …
pulmonary fibrosis, we used hFas-Fc in which the extracellular region of human Fas is fused to …
Differential Expression of VEGF-Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis
SL Barratt, T Blythe, C Jarrett, K Ourradi… - American journal of …, 2017 - atsjournals.org
… pulmonary fibrosis, ATII-specific deficiency of VEGF-A or constitutive overexpression of VEGF-A
165 b inhibited the development of pulmonary fibrosis… development of pulmonary fibrosis …
165 b inhibited the development of pulmonary fibrosis… development of pulmonary fibrosis …
[HTML][HTML] Prediction of the development of pulmonary fibrosis using serial thin-section CT and clinical features in patients discharged after treatment for COVID-19 …
… However it has rarely been reported whether discharged patients develop fibrosis, … pulmonary
fibrosis. In this study, we aimed to identify predictors for development of pulmonary fibrosis …
fibrosis. In this study, we aimed to identify predictors for development of pulmonary fibrosis …
[HTML][HTML] Pulmonary fibrosis: patterns and perpetrators
PW Noble, CE Barkauskas… - The Journal of clinical …, 2012 - Am Soc Clin Investig
… This type of pulmonary fibrosis has not been investigated rigorously, and this … of pulmonary
fibrosis. Thus, the ability to distinguish IPF and UIP from other forms of pulmonary fibrosis is of …
fibrosis. Thus, the ability to distinguish IPF and UIP from other forms of pulmonary fibrosis is of …