过去一年中添加的文章,按日期排序

Marigold: A machine learning-based web app for zebrafish pose tracking

G Teicher, RM Riffe, W Barnaby, G Martin, BE Clayton… - bioRxiv, 2024 - biorxiv.org
18 天前 - … Marigold features an intuitive graphical user interface (GUI), … loss-of-function mutation
in the gene encoding Eaat2b, a glial … and controlling for developmental stage and feeding …

FLT4 causes developmental disorders of the cardiovascular and lymphovascular systems via pleiotropic molecular mechanisms

RM Monaghan, RW Naylor, D Flatman… - Cardiovascular …, 2024 - academic.oup.com
43 天前 - … FLT4 TOF variants display characteristic gene expression profiles in key developmental
… of zebrafish flt4 morphants, highlighting the dose requirement for the gene during …

Development of an Automated Morphometric Approach to Assess Vascular Outcomes following Exposure to Environmental Chemicals in Zebrafish

X Zhong, J Chen, Z Zhang, Q Zhu, D Ji… - Environmental …, 2024 - ehp.niehs.nih.gov
47 天前 - … or potential etiology of developmental defects and various … a vessel–EC–gene–disease
strategy to integrate the … These results suggest that the vessel–EC–gene–disease …

A multiplexed transcriptomic analysis of a plant embryonic hourglass

H Wu, R Zhang, MJ Scanlon - bioRxiv, 2024 - biorxiv.org
74 天前 - gene expression in Drosophila, 13 zebrafish, and the flowering plant Arabidopsis,
featuring … the 806 expression level of each gene at developmental stage s, and the weighted …

Cross-species single-cell transcriptomics and its applications in evolutionary and translational research

D Keitley - 2024 - repository.cam.ac.uk
74 天前 - … to compare gene expression, cell types and developmental … challenges of relating
gene features and cell types, which … sea urchin, amphioxus and zebrafish embryo and offers a …

Biallelic variants in GTF3C5, a regulator of RNA polymerase III-mediated transcription, cause a multisystem developmental disorder

A Iwata-Otsubo, CM Skraban, A Yoshimura, T Sakata… - Human genetics, 2024 - Springer
88 天前 - … We injected each crRNA with Cas9 into zebrafish embryos and extracted DNA
from the fry at 5 days post-fertilization (dpf). We confirmed genomic aberrations at crRNA target …

Efficacy of Acetazolamide in Children with Chd2-Related Epilepsy: An Observational Study

G Melikishvili, T Gachechiladze, E Kurua, E Shojaeinia… - papers.ssrn.com
93 天前 - … chd2 in zebrafish larvae (referred to here as chd2 MO larvae), via microinjection of
an antisense morpholino oligomer targeting the zebrafish chd2 gene, caused developmental

Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation

S Kirchberger, MR Shoeb, D Lazic… - Nature …, 2024 - nature.com
113 天前 - … Finally, cross-species comparison enables the definition of a conserved gene
signature, which we apply to analyze bulk human tumor transcriptome data and to correlate …

Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt

JL Shepherdson, K Hutchison, DW Don… - The American Journal of …, 2024 - cell.com
135 天前 - … b-actin was used as a reference gene, and relative gene … in our cohort had
developmental delay, intellectual … to WT zebrafish during early developmental stages (Figure …

Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt

Genomics England Research … - American Journal of …, 2024 - research.manchester.ac.uk
135 天前 - … Exome or genome sequencing revealed 11 variants in 18 … Clinical findings
included developmental delay/… Additionally, a zebrafish model of ZFX loss displayed an altered …