Controlling acute inflammation with fast releasing dexamethasone-PLGA microsphere/PVA hydrogel composites for implantable devices
U Bhardwaj, R Sura… - Journal of diabetes …, 2007 - journals.sagepub.com
… microsphere/PVA hydrogel composites has been shown to suppress the inflammatory …
the initial acute inflammatory phase with fast releasing dexamethasone-PLGA microsphere/PVA …
the initial acute inflammatory phase with fast releasing dexamethasone-PLGA microsphere/PVA …
Dexamethasone/PLGA microspheres for continuous delivery of an anti-inflammatory drug for implantable medical devices
T Hickey, D Kreutzer, DJ Burgess, F Moussy - Biomaterials, 2002 - Elsevier
… In this paper, a new dexamethasone/PLGA microsphere system is reported which … release
of dexamethasone for over 1 month. This dexamethasone/PLGA microsphere system has …
of dexamethasone for over 1 month. This dexamethasone/PLGA microsphere system has …
In vivo evaluation of a dexamethasone/PLGA microsphere system designed to suppress the inflammatory tissue response to implantable medical devices
T Hickey, D Kreutzer, DJ Burgess… - Journal of Biomedical …, 2002 - Wiley Online Library
… dexamethasone/PLGA microsphere system to suppress both acute and chronic inflammatory
… proven the efficacy of PLGA microsphere delivery of an anti-inflammatory to control tissue …
… proven the efficacy of PLGA microsphere delivery of an anti-inflammatory to control tissue …
Evaluation of in vivo–in vitro release of dexamethasone from PLGA microspheres
BS Zolnik, DJ Burgess - Journal of controlled release, 2008 - Elsevier
… The in vivo pharmacodynamic affect of dexamethasone (ie control of inflammation at the
site) was also investigated in this study as this may affect the in vivo release kinetics. …
site) was also investigated in this study as this may affect the in vivo release kinetics. …
[HTML][HTML] Effect of dexamethasone-loaded PLGA nanoparticles on oral mucositis induced by 5-fluorouracil
SB Ribeiro, AA de Araújo, MMB Oliveira… - Pharmaceutics, 2021 - mdpi.com
… PLGA-DEX NPs 0.1 mg/kg group, compared to the 5-FU group. GILZ is considered a resolution
marker of the inflammatory … that the anti-inflammatory activity of DEX is associated with …
marker of the inflammatory … that the anti-inflammatory activity of DEX is associated with …
Downregulation of endotoxin-induced uveitis by intravitreal injection of polylactic-glycolic acid (PLGA) microspheres loaded with dexamethasone
E Barcia, R Herrero-Vanrell, A Díez… - Experimental eye …, 2009 - Elsevier
… dexamethasone-loaded microspheres had less inflammation than control eyes and eyes
injected with blank microspheres. Inflammation … Our dexamethasone-PLGA formulation was …
injected with blank microspheres. Inflammation … Our dexamethasone-PLGA formulation was …
Dexamethasone loaded PLGA nanoparticles for potential local treatment of oral precancerous lesions
S Rencber, F Aydın Köse… - Pharmaceutical …, 2020 - Taylor & Francis
… In conclusion, we expect that controlled release of DEX by this PLGA NP formulation will be
able to reduce inflammation for the local treatment of oral precancerous lesions and that the …
able to reduce inflammation for the local treatment of oral precancerous lesions and that the …
Dexamethasone-containing PLGA superparamagnetic microparticles as carriers for the local treatment of arthritis
N Butoescu, CA Seemayer, M Foti, O Jordan, E Doelker - Biomaterials, 2009 - Elsevier
… In our study, SPIONs and the corticosteroid dexamethasone acetate (DXM) are co-encapsulated
into PLGA microparticles for the aim of locally treating inflammatory conditions such as …
into PLGA microparticles for the aim of locally treating inflammatory conditions such as …
Co-delivery of dexamethasone and captopril by α8 integrin antibodies modified liposome-PLGA nanoparticle hybrids for targeted anti-inflammatory/anti-fibrosis …
L Zhou, Z Ye, E Zhang, L Chen, Y Hou… - International Journal …, 2022 - Taylor & Francis
… the anti-inflammatory and anti-fibrosis effect of DXMS/CAP@PLGA-ILs in the mouse MesPGN
model of this study. Hence, we measured the expression levels of inflammatory factors and …
model of this study. Hence, we measured the expression levels of inflammatory factors and …
In vitro and in vivo performance of dexamethasone loaded PLGA microspheres prepared using polymer blends
B Gu, Y Wang, DJ Burgess - International Journal of Pharmaceutics, 2015 - Elsevier
… events that include acute inflammation (eg., infiltration of inflammatory cells), chronic … low
Mw PLGA and the other with high Mw PLGA. Dexamethasone release from PLGA microspheres …
Mw PLGA and the other with high Mw PLGA. Dexamethasone release from PLGA microspheres …
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