Effect of pre-existing maternal obesity, gestational diabetes and adipokines on the expression of genes involved in lipid metabolism in adipose tissue

M Lappas - Metabolism, 2014 - Elsevier
… Lipoprotein lipase (LPL) regulates the hydrolysis of … triglyceride lipase (ATGL or PNPLA2),
hormone-sensitive lipase (… stored as fat and towards placenta where they would be oxidised …

Role of adipose tissue in regulating fetal growth in gestational diabetes mellitus

C Nguyen-Ngo, N Jayabalan, P Haghvirdizadeh… - Placenta, 2020 - Elsevier
Lipases, such as lipoprotein lipase (LPL) and endothelial lipase (EL), exist on the MVM to
catalyse the conversion of triglycerides into NEFAs [69,70], with activity thought to increase as …

Effects of maternal undernutrition and uterine artery ligation on placental lipase activities in the rat

S Kaminsky, SW D'souza, RF Massey, JL Smart… - Neonatology, 1991 - karger.com
Placental and fetal weights, fetal length, fetal lipid content, percentage placental pro tein and
placental lipase … by fetus or placenta then placental intracellular lipases may hydrolyse the …

The placenta in diabetic pregnancy: new methodological approaches

S Hauguel-de Mouzon, G Desoye - Gestational Diabetes, 2020 - karger.com
… Also, placental lipoprotein lipase methylation is altered in … in placenta of both pregestational
type 1 diabetes and GDM … Compared to GDM, type 1 diabetes mellitus induced fewer lipid …

[HTML][HTML] Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity

G Desoye, E Herrera - Progress in lipid research, 2021 - Elsevier
lipase in fetal adipose tissue. Its activity may be increased under hyperinsulinemic conditions
as in maternal diabetes mellitus … article to review maternal or placental lipid metabolism or …

Effect of type 2 diabetes mellitus on placental expression and activity of nutrient transporters and their association with birth weight and neonatal adiposity

M Castillo-Castrejon, K Yamaguchi, RL Rodel… - Molecular and cellular …, 2021 - Elsevier
… on placental insulin signaling, placental nutrient transporters and neonatal adiposity. …
placental function and is defined as birth weight/placental weight ratio. In our study, placental

Effect of maternal triglycerides and free fatty acids on placental LPL in cultured primary trophoblast cells and in a case of maternal LPL deficiency

AL Magnusson-Olsson, S Lager… - … Endocrinology and …, 2007 - journals.physiology.org
… Since the pH optimum of the placental specific lipase is 6.0, the activity of this lipase was …
lipase (EL) in syncytiotrophoblasts and mainly in endothelial cells along with LPL in placental

The human placenta in diabetes and obesity: friend or foe? The 2017 Norbert Freinkel Award Lecture

G Desoye - Diabetes care, 2018 - Am Diabetes Assoc
… The enzyme endothelial lipase (58) is the predominant lipase on the microvillous … low-grade
inflammation, which regulate endothelial lipase. The enzyme responds only when threshold …

Lipolytic activity in the placentas of chronically deprived fetuses

Y Biale - Acta obstetricia et gynecologica Scandinavica, 1985 - Wiley Online Library
… The existence of a high level of lipoprotein lipases in human placenta, as observed in our
series, may indicate that circulating maternal triglycerides have to be hydrolysed to FFA in the …

[HTML][HTML] Placental lipid processing in response to a maternal high-fat diet and diabetes in rats

EJ Louwagie, TD Larsen, AL Wachal, ML Baack - Pediatric research, 2018 - nature.com
… –placental–fetal triad remained unstudied. We hypothesized that HF diet would disrupt
placental lipid processing to exaggerate fuel-mediated consequences of diabetic pregnancy. …