Diabetes mellitus and its metabolic complications: the role of adipose tissues

L Dilworth, A Facey, F Omoruyi - International journal of molecular …, 2021 - mdpi.com
… , solidifies adipose tissue role in the development and pathogenesis of diabetes mellitus and
… This review will highlight the role of adipose tissue in the pathogenesis of diabetes and the …

The importance of adipose tissue in diabetes pathophysiology and treatment

G Dimitriadis, E Boutati… - Hormone and Metabolic …, 2007 - thieme-connect.com
Adipose tissue provides its buffering action by … Adipose tissue buffering of lipid fluxes is
impaired in obesity and type 2 diabetes through defects in the ability of adipose tissue to respond …

Role of adipose tissue in the development of vascular complications in type 2 diabetes mellitus

I Kowalska - Diabetes Research and Clinical Practice, 2007 - Elsevier
… The pathogenic role of adipose tissue depends also on its localisation. The subcutaneous
adipose tissue serves mainly as an energy depot, whereas the visceral fat influences the …

The multifaceted roles of adipose tissue—therapeutic targets for diabetes and beyond: The 2015 Banting Lecture

PE Scherer - Diabetes, 2016 - Am Diabetes Assoc
… To probe further into the role of the inflammatory response in adipose tissue physiology, we
… anti-inflammatory activity, exclusively at the level of the adipocyte (17). We have done this in …

Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

GR Hajer, TW Van Haeften… - European heart …, 2008 - academic.oup.com
… of adipose tissue function is the quantity of visceral fat. The objective of this paper is to
describe adipose tissue dysfunction, delineate the relation between adipose tissue dysfunction …

Endocrine functions of adipose tissue

H Waki, P Tontonoz - Annu. Rev. Pathol. Mech. Dis., 2007 - annualreviews.org
role in each component of the syndrome (2). However, it is not yet clear how excess fat in
adipose tissue … the spectrum, patients and mice that lack normal adipose tissue, a pathological …

Adipose tissue macrophages: their role in adipose tissue remodeling

T Suganami, Y Ogawa - Journal of leukocyte biology, 2010 - academic.oup.com
… -related gene expression in the adipose tissue precede the development of insulin … the
adipose tissue. This review summarizes the role of macrophages in adipose tissue inflammation. …

The endocrine function of adipose tissue: an update

T Ronti, G Lupattelli, E Mannarino - Clinical endocrinology, 2006 - Wiley Online Library
… Third, increased fat cell size is associated with insulin resistance and diabetes. Large fat
cells may underlie the failure of the adipose tissue mass to expand and accommodate a high …

The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes

K Cusi - Current diabetes reports, 2010 - Springer
diabetes mellitus (T2DM) suggest that both conditions are closely linked. An increasing body
of evidence has shifted our view of adipose tissue … Dysfunctional adipose tissue, particularly …

Differential role of adipose tissues in obesity and related metabolic and vascular complications

A Gómez-Hernández, N Beneit… - International journal …, 2016 - Wiley Online Library
role of perivascular adipose tissue (PVAT) in obesity and mainly its action in the associated
vascular complications. This tissue is … or less characteristics of white or brown adipose tissue. …