Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

DIAbetes Genetics Replication And Meta-analysis  … - Nature …, 2014 - nature.com
… of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-…
By following up the strongest signals of association from the trans-ethnic meta-analysis in …

Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes

PJ Hale, AM López-Yunez, JY Chen - BMC systems biology, 2012 - Springer
Background Many genetic studies, including single gene studies and Genome-wide association
studies (GWAS), aim to identify risk alleles for genetic diseases such as Type II Diabetes

Association between polymorphisms in microRNAs and susceptibility to diabetes mellitus: A meta-analysis

X Chen, W Wang, R Li, J Yu, L Gao - Medicine, 2019 - journals.lww.com
Background: Accumulated evidence has indicated the associations between single-nucleotide
polymorphisms (SNPs) in microRNAs (miRNAs) and the susceptibility to diabetes mellitus …

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini… - Nature …, 2008 - nature.com
… variants modestly but reproducibly influence risk of type 2 diabetes (T2D) 1 , 2 , 3 , 4 , 5 , …
analyses had limited power to identify variants with modest effects, we carried out meta-analysis

… between TCF7L2gene polymorphisms and susceptibility to Type 2 Diabetes Mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis

Y Tong, Y Lin, Y Zhang, J Yang, Y Zhang, H Liu… - BMC medical …, 2009 - Springer
Background Transcription factor 7-like 2 (TCF7L2) has been shown to be associated with
type 2 diabetes mellitus (T2MD) in multiple ethnic groups in the past two years, but, …

Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility

MN Weedon, PEH Schwarz, Y Horikawa… - The American Journal of …, 2003 - cell.com
Variation in the calpain-10 gene (CAPN10 [MIM 605286]) was recently linked and associated
with type 2 diabetes mellitus (T2DM) susceptibility (Horikawa et al. 2000). The initial …

Genetic susceptibility to type 2 diabetes: a global meta-analysis studying the genetic differences in Tunisian populations

R Berhouma, S Kouidhi, M Ammar, H Abid, T Baroudi… - Human biology, 2012 - BioOne
… polymorphisms between diabetic patients and controls were selected. The articles with
incomplete data were not included in our meta-analysis. The aim of our meta-analysis was to …

Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis

FK Kavvoura, JPA Ioannidis - Human genetics, 2005 - Springer
… of those included in this meta-analysis specified that auto-… Thus, it may indeed have no
effect on diabetes susceptibility, … We should also caution that, even though the meta-analysis

Vitamin D Receptor gene polymorphisms and susceptibility to type 2 diabetes: evidence from a meta-regression and meta-analysis based on 47 studies

S Aravindhan, MFM Almasoody, NA Selman… - Journal of Diabetes & …, 2021 - Springer
… VDR gene SNPs and susceptibility of T2D. The results of the meta-analysis demonstrated
that FokI polymorphism in the overall analysis increased the susceptibility of T2D according to …

CTLA-4 Gene Polymorphisms and Susceptibility to Type 1 Diabetes Mellitus: A HuGE Review and Meta-Analysis

FK Kavvoura, JPA Ioannidis - American journal of epidemiology, 2005 - academic.oup.com
meta-analysis demonstrates that the CTLA-4*G genotype is associated with type 1 diabetes.
… It is considered the most likely candidate gene for type 1 diabetes susceptibility for the …