Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
DIAbetes Genetics Replication And Meta-analysis … - Nature …, 2014 - nature.com
… risk alleles across ancestry groups, even … trans-ethnic meta-analysis in an additional 21,491
cases and 55,647 controls of European ancestry, we identified seven new T2D susceptibility …
cases and 55,647 controls of European ancestry, we identified seven new T2D susceptibility …
[PDF][PDF] Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
N Genet - Nat Genet, 2014 - academia.edu
… T2D risk alleles across ancestry groups, … trans-ethnic metaanalysis in an additional 21,491
cases and 55,647 controls of European ancestry, we identified seven novel T2D susceptibility …
cases and 55,647 controls of European ancestry, we identified seven novel T2D susceptibility …
… to assess the association of commonly used antihypertensive drugs with diabetes, glycaemic traits and lipids: a trans-ancestry Mendelian randomisation study
… In the era of evidence-based medicine, our findings from a large trans-ancestry MR provide
another piece of evidence complementary to clinical trials, as references for hypertension …
another piece of evidence complementary to clinical trials, as references for hypertension …
Fine mapping of type 2 diabetes susceptibility loci
AP Morris - Current diabetes reports, 2014 - Springer
… susceptibility in European ancestry populations. … diabetes susceptibility. Nat Genet.
2014;46:234–44. This manuscript reports the largest trans-ethnic meta-analysis for T2D …
2014;46:234–44. This manuscript reports the largest trans-ethnic meta-analysis for T2D …
Trans-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
… for T2D susceptibility. Association summary statistics for GDM were obtained from trans-ancestry …
Association summary statistics for T2D were obtained from trans-ancestry GWAS meta-…
Association summary statistics for T2D were obtained from trans-ancestry GWAS meta-…
Impact of the trans-ancestry polygenic risk score on type 2 diabetes risk, onset age and progression among population in Taiwan
SH Wang, YC Huang, CW Cheng… - American Journal …, 2024 - journals.physiology.org
… Our findings suggest that diabetic susceptibility variants affect the onset age of 229 T2D.
Individuals who carried a greater risk of allele load (in the top 10% of the PRS distribution) 230 …
Individuals who carried a greater risk of allele load (in the top 10% of the PRS distribution) 230 …
Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity
JF Shelton, AJ Shastri, C Ye, CH Weldon… - Nature Genetics, 2021 - nature.com
… Using trans-ancestry genome-wide association studies, we identified a strong association …
European ancestry and preexisting cardiometabolic conditions. While non-European ancestry …
European ancestry and preexisting cardiometabolic conditions. While non-European ancestry …
Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility
JP Cook, AP Morris - European Journal of Human Genetics, 2016 - nature.com
… effects on T2D susceptibility between ancestry groups for lead … trans-ethnic meta-analysis
of T2D susceptibility GWAS that highlighted heterogeneous allelic effects between ancestry …
of T2D susceptibility GWAS that highlighted heterogeneous allelic effects between ancestry …
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms
M Horikoshi, L Pasquali, S Wiltshire… - Human molecular …, 2016 - academic.oup.com
… of variants at four established type 2 diabetes (T2D) susceptibility loci (CDKAL1, CDKN2A-B…
with allelic effects on T2D susceptibility that were homogenous across ancestry groups. By …
with allelic effects on T2D susceptibility that were homogenous across ancestry groups. By …
Genetics of type 2 diabetes in African Americans
MCY Ng - Current diabetes reports, 2015 - Springer
… in trans-ancestry meta-analysis [54••]. Future studies that include African Americans in
trans-ancestry meta-… Insights into the genetic susceptibility to type 2 diabetes from genome-wide …
trans-ancestry meta-… Insights into the genetic susceptibility to type 2 diabetes from genome-wide …
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