… of developmental retardation and litter size in pregnant diabetic mice. FVB females were
made diabetic … In brief, animals to be treated with streptozotocin were randomly chosen. The …

… diabetic states and which is responsible for some metabolic complications in diabetics, is the
… vivo studies examining the offspring of diabetic animals and the effects of administration of …

… the diabetic group, but the variation among gravida precluded statistical significance (31 ± 4
g in the diabetic groups versus 39 ± 2 g in the control animals… , diabetic animals displayed a …

… early growth retardation, delayed morphogenetic and biochemical developmental sequences,
… and growth, offspring of moderate or severe diabetic animals had an increased incidence …

… Both genetic and acquired reductions in Pdx1 expression in humans and in animal models
have been shown to cause type 2 diabetes, β cell dysfunction (7–14), and impaired islet …

… from diabetic animals, which may impact negatively on subsequent developmental capacity.
… Furthermore, abnormal placentation, fetal growth retardation, death and premature delivery …

… diabetes. Whereas macrosomia often occurs in infants of diabetic women, growth retardation
is almost a rule in spontaneous and experimental diabetes in animals. However, it is not …

… retardation at 7-14 weeks of gestation in infants of diabetic … induced and spontaneous diabetic
animal models (Lawrence & … -diabetic littermates as direct controls for the diabetic animals…

… demonstrated in animal models, where type 1 diabetes is induced by injecting animals with
… the children who did not suffer in utero from growth retardation were normal. Hod et al. (2001…

… While this was only a single value, and was obtained in animals which had had free access
… of diabetes mellitus, and thus less severe metabolic derangements. This growth retardation …