Changes in N6-methyladenosine modification modulate diabetic cardiomyopathy by reducing myocardial fibrosis and myocyte hypertrophy
W Ju, K Liu, S Ouyang, Z Liu, F He… - Frontiers in Cell and …, 2021 - frontiersin.org
… global RNA N6-methyladenosine (m 6 A) modification patterns in a mouse model of diabetic
cardiomyopathy (DCM). Patterns of m 6 A in DCM and normal hearts were analyzed via m 6 …
cardiomyopathy (DCM). Patterns of m 6 A in DCM and normal hearts were analyzed via m 6 …
N6-Methyladenosine-mediated phase separation suppresses NOTCH1 expression and promotes mitochondrial fission in diabetic cardiac fibrosis
ZY Liu, LC Lin, ZY Liu, K Song, B Tu, H Sun… - Cardiovascular …, 2024 - Springer
… NOTCH1 was reconstituted in ALKBH5- and YTHDF2-deficient cardiac fibroblasts and …
and diabetic cardiac fibrosis. Heart tissue samples from patients with diabetic cardiomyopathy …
and diabetic cardiac fibrosis. Heart tissue samples from patients with diabetic cardiomyopathy …
N6-Adenosine Methylation (m6A) RNA Modification: an Emerging Role in Cardiovascular Diseases
Y Chen, X Ouyang, X Yu, P Novák, L Zhou… - Journal of …, 2021 - Springer
… N6-methyladenosine (m 6 A) is the most abundant and … However, the exact roles of m 6
A in cardiovascular diseases (… m 6 A methylation in the progress of CVDs, such as cardiac …
A in cardiovascular diseases (… m 6 A methylation in the progress of CVDs, such as cardiac …
[HTML][HTML] N6-Methyladenosine in vascular aging and related diseases: clinical perspectives
C Li, L Liu, S Li, YS Liu - Aging and Disease, 2024 - pmc.ncbi.nlm.nih.gov
… N 6 -methyladenosine (m 6 A) is the most prevalent modification in eukaryotic RNAs. This
reversible m 6 A RNA modification is dynamically regulated by writers, erasers, and readers, …
reversible m 6 A RNA modification is dynamically regulated by writers, erasers, and readers, …
METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA
L Meng, H Lin, X Huang, J Weng, F Peng, S Wu - Cell death & disease, 2022 - nature.com
… N6-methyladenosine (m6A) is one of the most important epigenetic regulation of RNAs, …
However, the underlying regulatory mechanism of m6A in diabetic cardiomyopathy (DCM) is …
However, the underlying regulatory mechanism of m6A in diabetic cardiomyopathy (DCM) is …
[HTML][HTML] Unravelling the Impact of RNA Methylation Genetic and Epigenetic Machinery in the Treatment of Cardiomyopathy
L Liu, L Yu, Y Wang, L Zhou, Y Liu, X Pan… - Pharmacological …, 2024 - Elsevier
… N6-methyladenosine (m6A), 5-methylcytosine (m5C), N7-methylguanosine (m7G), N1-methyladenosine
(m1A), 2'-O-methylation (Nm), and 6,2'-… In the context of diabetic cardiac fibrosis, …
(m1A), 2'-O-methylation (Nm), and 6,2'-… In the context of diabetic cardiac fibrosis, …
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis
T Peng, M Liu, L Hu, D Guo, D Wang, B Qi, G Ren… - Biology Direct, 2022 - Springer
… dysfunction in patients with diabetes. However, the underlying mechanisms of cardiac
fibrosis … of cardiac fibrosis in diabetic cardiomyopathy (DCM) and its underlying mechanism. …
fibrosis … of cardiac fibrosis in diabetic cardiomyopathy (DCM) and its underlying mechanism. …
Regulation of N6-methyladenosine after myocardial infarction
M Vausort, M Niedolistek, AI Lumley, M Oknińska… - Cells, 2022 - mdpi.com
… The functional association between the regulation of m6A levels in blood and cardiac
dysfunction remains to be established, yet our data showing a positive correlation with cardiac …
dysfunction remains to be established, yet our data showing a positive correlation with cardiac …
N6-methyladenosine RNA methylation in cardiovascular diseases
C Liu, L Gu, W Deng, Q Meng, N Li, G Dai… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosine (m6A) modification is the most universal and abundant post-transcriptional
modification of eukaryotic RNA and occurs mainly at the consensus motif RR (m6A) CH (…
modification of eukaryotic RNA and occurs mainly at the consensus motif RR (m6A) CH (…
[HTML][HTML] N 6‐methyladenine profiling of low‐input multiplex clinical samples on transcriptome reveals RNA modifications implicated in type 2 diabetes and acute …
S Qin, K Yang, S Han, Y Yuan, J Mo… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Dear Editor, RNA N6-methyladenines (m6A) not only play an essential role in normal biological
processes but also participate in the pathogenesis of diseases including type 2 diabetes …
processes but also participate in the pathogenesis of diseases including type 2 diabetes …
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