[HTML][HTML] Curcumin, a polyphenolic curcuminoid with its protective effects and molecular mechanisms in diabetes and diabetic cardiomyopathy

J Zheng, J Cheng, S Zheng, Q Feng… - Frontiers in …, 2018 - frontiersin.org
… variety of diseases, including diabetes and its … curcumin supplementation on diabetes and
DCM are presented, and the specific mechanisms by which curcumin might mitigate diabetes

Tiny molecule, big power: multi-target approach for curcumin in diabetic cardiomyopathy

V Karuppagounder, S Arumugam, VV Giridharan… - Nutrition, 2017 - Elsevier
Curcumin (diferuloylmethane) a natural polyphenol present in the popular Indian spice
turmeric, belongs to the ginger family. Traditionally turmeric has been widely used in Ayurveda …

Curcumin protects against diabetic cardiomyopathy by promoting autophagy and alleviating apoptosis

Q Yao, Z Ke, S Guo, X Yang, F Zhang, X Liu… - Journal of molecular and …, 2018 - Elsevier
Curcumin is a naturally occurring polyphenol isolated from … that curcumin prevents diabetic
cardiomyopathy by … the protective roles of curcumin in diabetic cardiomyopathy. In addition, …

Curcumin alleviates oxidative stress and inhibits apoptosis in diabetic cardiomyopathy via Sirt1‐Foxo1 and PI3K‐Akt signalling pathways

B Ren, Y Zhang, S Liu, X Cheng, X Yang… - Journal of cellular …, 2020 - Wiley Online Library
Curcumin is a natural polyphenol isolated from the root of Curcuma longa, … curcumin
including alleviating myocardial apoptosis and improving cardiac function in experimental diabetic

[HTML][HTML] Pathophysiology, clinical characteristics of diabetic cardiomyopathy: Therapeutic potential of natural polyphenols

N Atale, D Yadav, V Rani, JO Jin - Frontiers in Nutrition, 2020 - frontiersin.org
polyphenols tested in preclinical and cell culture models of diabetic cardiomyopathy.
Further, the potential use of selected polyphenols that improved the therapeutic efficacy against …

[HTML][HTML] An examination of the protective effects and molecular mechanisms of curcumin, a polyphenol curcuminoid in diabetic nephropathy

X Zhu, X Xu, C Du, Y Su, L Yin, X Tan, H Liu… - Biomedicine & …, 2022 - Elsevier
… of curcumin, a polyphenol curcuminoid, have been demonstrated in research on diabetic
nephropathy. The clinical and preclinical trials and mechanisms by which curcumin affects DN …

Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC–MAPK signaling pathway

V Soetikno, FR Sari, V Sukumaran… - European Journal of …, 2012 - Elsevier
… of curcumin on ameliorating diabetic cardiomyopathy are still undefined. We evaluated
whether curcumin … protein kinase (MAPK) pathway in experimental diabetic cardiomyopathy. …

[HTML][HTML] The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy

H Bhagani, SA Nasser, A Dakroub, AF El-Yazbi… - International Journal of …, 2020 - mdpi.com
… In addition, polyphenols have been shown to improve the progression of diabetes. In this
review, we discuss some of the mechanisms by which polyphenols, particularly resveratrol, …

[HTML][HTML] Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats

W Yu, J Wu, F Cai, J Xiang, W Zha, D Fan, S Guo… - PloS one, 2012 - journals.plos.org
… effects of curcumin on alterations of cardiac function and morphology in diabetic rats, and the
Curcumin is the most abundant polyphenol present in the dietary spice turmeric. In addition …

Cardioprotective effect of pioglitazone and curcumin against diabetic cardiomyopathy in type 1 diabetes mellitus: impact on CaMKII/NF-κB/TGF-β1 and PPAR-γ …

AA Gbr, NA Abdel Baky, EA Mohamed… - … Archives of Pharmacology, 2021 - Springer
Curcumin (Cur) is a polyphenol that represents the major active compound in Curcuma
longa. It possesses many biological activities such as antioxidant, antineoplastic, antiproliferative…