Akebia Saponin D ameliorated kidney injury and exerted anti-inflammatory and anti-apoptotic effects in diabetic nephropathy by activation of NRF2/HO-1 and …
C Lu, G Fan, D Wang - International Immunopharmacology, 2020 - Elsevier
… Diabetic nephropathy (DN), a common microvascular complication of type 2 diabetes …
This study was designed to investigate the critical role of Akebia saponin D (ASD) in kidney …
This study was designed to investigate the critical role of Akebia saponin D (ASD) in kidney …
[HTML][HTML] Administration of Akebia Saponin D Improved Blood Lipid Levels and Pregnancy Outcomes in Mice with Gestational Diabetes Mellitus
W Chen, J Shi, W Zhang - Balkan Medical Journal, 2023 - ncbi.nlm.nih.gov
… isolated from the Radix Dipsaci, 13 has been shown to reduce blood glucose and increase
insulin levels in diabetic nephropathy mice. Consistently, ASD reduced body weight, …
insulin levels in diabetic nephropathy mice. Consistently, ASD reduced body weight, …
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice
M Gu, J Jin, C Ren, X Chen, W Gao, X Wang, Y Wu… - Food & function, 2020 - pubs.rsc.org
… Akebia Saponin D (ASD) is a main active component … that Akebia Saponin D suppresses
the NF-KB pathway by activating NRF2/HO-1, improves kidney damage in diabetic nephropathy…
the NF-KB pathway by activating NRF2/HO-1, improves kidney damage in diabetic nephropathy…
Akebia saponin D attenuates allergic airway inflammation through AMPK activation
L Xuan, S Yang, L Ren, H Liu, W Zhang, Y Sun… - Journal of Natural …, 2024 - Springer
… Akebia saponin D (ASD), a triterpenoid saponin extracted from root of Dipsacus asper Wall.
ex DC., exhibited protective effects on many disorders, including hyperlipidemia, Alzheimer’…
ex DC., exhibited protective effects on many disorders, including hyperlipidemia, Alzheimer’…
… nephropathy progression via mitigating renal oxidative stress, inflammation, fibrosis and apoptosis in high fat diet and low dose streptozotocin-induced diabetic rats
NA Abd Wahab, N Giribabu, EK Kilari, N Salleh - Phytomedicine, 2022 - Elsevier
… Diabetic nephropathy (DN) is one of the complications of diabetes mellitus (DM), which can
… Suggested mechanisms of AA protective effect against diabetic nephropathy. As a result of …
… Suggested mechanisms of AA protective effect against diabetic nephropathy. As a result of …
Integrated network pharmacology and pharmacological investigations to discover the active compounds of Toona sinensis pericarps against diabetic nephropathy
H Li, R Wang, Y Chen, M Zhao, S Lan, C Zhao… - Journal of …, 2024 - Elsevier
… Diabetic nephropathy (DN) is the leading reason of chronic kidney disease, and one of the
… to visualize the overlap between the targets of TCMSP prediction and Diabetic Nephropathy. …
… to visualize the overlap between the targets of TCMSP prediction and Diabetic Nephropathy. …
Akebia trifoliata pericarp extract ameliorates inflammation through NF-κB/MAPK signaling pathways and modifies gut microbiota
X Wang, N Yu, Z Wang, T Qiu, L Jiang, X Zhu, Y Sun… - Food & function, 2020 - pubs.rsc.org
… In addition, previous research showed that triterpenoid is the main component of Akebia,
and our research also proves this point. About 10 types of saponins were tentatively identified …
and our research also proves this point. About 10 types of saponins were tentatively identified …
Herbal nephropathy
R Claure-Del Granado… - Nephrology and Public …, 2021 - karger.com
… longepedunculata (violet tree) that contains methyl salicylate and saponin; Euphorbia … to
diabetic nephropathy [41– 43]. Khajehdehi et al. [44] randomized diabetic nephropathy patients …
diabetic nephropathy [41– 43]. Khajehdehi et al. [44] randomized diabetic nephropathy patients …
Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases
B Han, C He - Pharmacological Research, 2021 - Elsevier
… some saponins are reported to modulate autophagy. Research suggests that saponins may
… Therefore, this review comprehensively summarizes and discusses the reported saponins …
… Therefore, this review comprehensively summarizes and discusses the reported saponins …
Bioactive compounds effective against type 2 diabetes mellitus: a systematic review
… may be induced by type 2 diabetes mellitus. Some acute complications (diabetic retinopathy,
diabetic nephropathy, diabetic neuropathy) are mainly connected to high mortality in …
diabetic nephropathy, diabetic neuropathy) are mainly connected to high mortality in …
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