[HTML][HTML] Diabetes regulates mitochondrial biogenesis and fission in mouse neurons

JL Edwards, A Quattrini, SI Lentz, C Figueroa-Romero… - Diabetologia, 2010 - Springer
… Despite the neuroprotective effects of mitochondrial biogenesis, its role in diabetic neuropathy
is not well characterised. Current theory suggests that increased mitochondrial biogenesis

Mitochondrial biogenesis and the development of diabetic retinopathy

JM Santos, S Tewari, AFX Goldberg… - Free Radical Biology and …, 2011 - Elsevier
… of diabetes on mitochondrial biogenesis in the retina and the role of mitochondrial biogenesis
in the development of retinopathy… damage, mitochondrial biogenesis was examined in the …

Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy

AM Vincent, JL Edwards, LL McLean, Y Hong… - Acta …, 2010 - Springer
… These findings led us to examine mitochondrial biogenesis and fission in … mitochondrial
biogenesis via increases in mitochondrial transcription factors and increases in mitochondrial

Mitochondrial stress and the pathogenesis of diabetic neuropathy

P Fernyhough, SK Roy Chowdhury… - Expert review of …, 2010 - Taylor & Francis
Diabetic neuropathy is a major complication of diabetes that affects the sensory and …
Mitochondrial stress has been proposed as a major mediator of neurodegeneration in diabetes. This …

SIRT1 activation by polydatin alleviates oxidative damage and elevates mitochondrial biogenesis in experimental diabetic neuropathy

P Bheereddy, VG Yerra, AK Kalvala… - Cellular and molecular …, 2021 - Springer
… that deficits in mitochondrial biogenesis have a vital role in the pathogenesis of DN and
SIRT1 activation reversed this condition by inducing mitochondrial biogenesis. These findings …

[HTML][HTML] Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid

JM Santos, RA Kowluru - Investigative ophthalmology & visual …, 2011 - iovs.arvojournals.org
… function, and with mitochondrial number and size, 16 and our recent studies have … of diabetic
retinopathy, retinal mitochondria biogenesis is impaired and the number of mitochondria is …

[HTML][HTML] … as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

D Zhou, M Zhou, Z Wang, Y Fu, M Jia, X Wang… - Cell death & …, 2019 - nature.com
… Considering that histone deacetylase Sirt1 is extensively implicated in both mitochondrial
biogenesis and mitophagy, we then measured the levels of Sirt1 and other sirtuin members in …

… hyperglycaemia-induced neuronal injury in experimental models of diabetic neuropathy: effects on mitochondrial biogenesis, autophagy and neuroinflammation

VG Yerra, A Kumar - Molecular neurobiology, 2017 - Springer
… related to diabetes. The present study assesses the role of AMPK activation on mitochondrial
biogenesis, autophagy and neuroinflammation in experimental diabetic neuropathy (DN) …

Posttranslational modification of mitochondrial transcription factor A in impaired mitochondria biogenesis: implications in diabetic retinopathy and metabolic memory …

JM Santos, M Mishra, RA Kowluru - Experimental eye research, 2014 - Elsevier
… Hsp70 might not be the major factor responsible for chaperoning TFAM to the mitochondria.
mitochondria biogenesis is decreased in diabetes. However, despite decrease in biogenesis

[HTML][HTML] Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice

JA Fields, MK Swinton, A Carson, B Soontornniyomkij… - Scientific reports, 2019 - nature.com
mitochondria in neurons. In this study, we hypothesized that TDF contributes to neurotoxicity
by modulating mitochondrial biogenesis … ) mice caused peripheral neuropathy, as indicated …