Antihyperglycemic action of isoferulic acid in streptozotocin‐induced diabetic rats

IM Liu, FL Hsu, CF Chen… - British Journal of …, 2000 - Wiley Online Library
rats and STZ-diabetic rats and that isoferulic acid caused an increase in both 2-DG uptake
and … incorporation in the STZ-diabetic rats. The effects of isoferulic acid on 2-DG uptake and …

Mediation of β-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats

IM Liu, WC Chen, JT Cheng - Journal of Pharmacology and Experimental …, 2003 - ASPET
Isoferulic acid can activate α 1A -adrenoceptor… isoferulic acid is still unclear. Thus, we
investigated the mechanisms by which isoferulic acid reduces plasma glucose level in diabetic rats

[HTML][HTML] Isoferulic acid attenuates methylglyoxal-induced apoptosis in INS-1 rat pancreatic β-cell through mitochondrial survival pathways and increasing glyoxalase-1 …

A Meeprom, CB Chan, W Sompong… - Biomedicine & …, 2018 - Elsevier
acid and its derivatives have received increasing attention in recent years due to their biological
activities [12]. Isoferulic acid (IFA), a naturally occurring cinnamic acid, … diabetic rats [14]. …

Isoferulic Acid, a New Anti-Glycation Agent, Inhibits Fructose- and Glucose-Mediated Protein Glycation in Vitro

A Meeprom, W Sompong, CB Chan, S Adisakwattana - Molecules, 2013 - mdpi.com
… ], and anti-diabetic properties [23]. Interestingly, the administration of isoferulic acid (IFA)
reduces plasma glucose concentration in streptozotocin-induced diabetic rats by activating α 1 -…

Phytochemical Identification and Anti-Oxidative Stress Effects Study of Cimicifugae Rhizoma Extract and Its Major Component Isoferulic Acid

J Liu, A Chang, H Peng, X Yin, X Dong, C Qu, J Ni - Separations, 2024 - mdpi.com
… the treatment of diabetes [11]. In the subsequent investigation of Isoferulic acid, it was
determined that the decline in plasma glucose levels in streptozotocin -diabetic rats might perhaps …

… and pharmacokinetics of isoferulic acid in rat plasma by high-performance liquid chromatography after oral administration of isoferulic acid and Rhizoma Cimicifugae …

D Si, X Sun, D Qi, X Chen, K Bi - Journal of pharmaceutical and biomedical …, 2008 - Elsevier
… spontaneously diabetic BioBreeding/Worcester (BB/W) rats [2]… in streptozotocin-induced
diabetic rats (STZ-diabetic rats) [3], … isoferulic acid could be effective for the treatment of diabetes […

Inhibition of advanced glycation end products by isoferulic acid and its free radical scavenging capacity: An in vitro and molecular docking study

S Arfin, GA Siddiqui, A Naeem, S Moin - International journal of biological …, 2018 - Elsevier
diabetes and atherosclerosis. Hyperglycemia plays a key role in the pathological process of
diabetic … free radical scavenging and antiglycation capacity of isoferulic acid (IFA). The free …

A series of cinnamic acid derivatives and their inhibitory activity on intestinal α-glucosidase

S Adisakwattana, P Chantarasinlapin… - Journal of Enzyme …, 2009 - Taylor & Francis
acid derivatives, caffeic acid, ferulic acid, and isoferulic acid … Furthermore, isoferulic acid
significantly decreases the levels … (STZ)-induced diabetic rats by suppression of hepatic …

Glycation derived AuNPs bioconjugated novel herbal drug isoferulic acid: As a potential anti-glycation, anti-diabetic and antineoplastic agent

Z Rafi, M Khan, S Khan, M Srivastava, S Haque… - Colloids and Surfaces A …, 2023 - Elsevier
… It has also been observed that it cuts glucose levels plasma in diabetic rats (streptozotocin-derived
by activating α1-adrenoceptors to augment the secretion of β-endorphin, responsible …

Ferulic acid prevents pathological and functional abnormalities of the kidney in Otsuka Long-Evans Tokushima Fatty diabetic rats

A Fujita, H Sasaki, A Doi, K Okamoto, S Matsuno… - Diabetes research and …, 2008 - Elsevier
… (LETO) rats were used as type 2 diabetes and non-diabetes models, respectively. Two-thirds
of the OLETF rats were fed 0.2% FA-containing or 0.5% AT-containing chow. Diabetic