… Effect of BCA on Renal NLRP3/Caspase-1 Signaling Axis in Diabetic Kidneys Further,
we studied the NLRP3 inflammasome signaling in diabetic kidneys. As depicted in Figure 8, …

… injury was detected in diabetic rats associated with the over expression of pyroptotic-related
proteins (TXNIP and NLRP3). On the other hand, in calycosin treated rats, renal damages …

… NLRP3 protein expression, predominantly located in the axons of SNs in diabetic rats ( Figure
5A – D ), was increased in the diabetic … effects of diabetes on NLRP3 protein expression ( …

… The aim of this study was to evaluate the analgesic effect of salidroside on diabetic rats and
… pain in diabetic rats. Specifically, regulation of the AMPK-NLRP3 inflammasome axis was …

… axis was shown to induce the formation of the NLRP3 … axis in the regulation of the NLRP3
inflammasome in DCM. … /CMKLR1 axis in DCM rats, and whether the NLRP3 inflammasome is …

… NLRP3, indicating that ROS-TXNIP may be the target of TSF. In summary, the anti-pyroptotic
effect via the TXNIP-NLRP3-GSDMD axis … renal injuries in DKD rats accompanied by the …

… the NLRP3 axis and reduced renal damage in DN rats. ERS was activated in DN rats, and
… DN rats, and stimulates the TXINP/NLRP3 pathway-mediated pyroptosis and renal damage. …

… involved in AMPK/mTOR/NLRP3 axis and T Cell polarization. … and depressed mTOR and
NLRP3 expression leading to a … Since adult humans with diabetes mellitus are at greater risk …

… may stem from the inhibition of both pro-inflammatory cytokines and HIF-1α/VEGF axis. … In
brief, we highlight a protective role of the NLRP3 blockade in the in vivo rat model of DR. Down-…

… However, as hyperlipidemia is present in type 2 diabetes, we measured serum TG and
TC levels of DN rats and used Oil Red O staining to visualize renal lipopathy. As depicted in …