Proteomic changes associated with diabetes in the BB-DP rat

DT Johnson, RA Harris, S French… - American Journal …, 2009 - journals.physiology.org
Proteomics was used in this study to semiquantitate changes … that might reveal metabolic
changes in type 1 diabetes that are … In the diabetes model used, the most dramatic proteomic

Alteration of the proteome profile of the pancreas in diabetic rats induced by streptozotocin

YL Jiang, Y Ning, XL Ma, YY Liu… - International …, 2011 - spandidos-publications.com
Proteomics is a powerful tool to describe changes in protein expression and modification, …
out proteomic analysis of the pancreas of diabetic Sprague-dawley (Sd) rats induced by STZ…

Temporal transcriptomic and proteomic landscapes of deteriorating pancreatic islets in type 2 diabetic rats

J Hou, Z Li, W Zhong, Q Hao, L Lei, L Wang, D Zhao… - Diabetes, 2017 - Am Diabetes Assoc
… tag–based quantitative proteomics technology to measure … changes of pancreatic islets in
Goto-Kakizaki (GK) rats from 4 to … and proteome data offer a valuable resource for the diabetes

Stage-specific quantitative changes in renal and urinary proteome during the progression and development of streptozotocin-induced diabetic nephropathy in rats

V Sharma, K Tikoo - Molecular and cellular biochemistry, 2014 - Springer
… an analysis of parallel proteomic changes in the renal proteome. Hence, we devised our
strategy to find out the changes in the urinary proteome from normal and diabetic rats during the …

[HTML][HTML] Differential proteomic analyses of cataracts from rat models of type 1 and 2 diabetes

S Su, F Leng, L Guan, L Zhang, J Ge… - … & Visual Science, 2014 - tvst.arvojournals.org
… 2 diabetic rat model and the conventional type 1 diabetic rat model (induced with relatively
high doses of STZ) to perform proteomic … and differential biochemical changes in both types of …

Liver proteome in diabetes type 1 rat model: Insulin-dependent and-independent changes

CP Braga, CHT Boone, RA Grove… - Omics: a journal of …, 2016 - liebertpub.com
… on the hepatic proteome, streptozotocin (STZ) was used to induce DM1 in a rat model. This
is a … Although STZ-induced proteomic studies have been published, the subset of proteins …

Proteomics of the rat myocardium during development of type 2 diabetes mellitus reveals progressive alterations in major metabolic pathways

AV Edhager, JA Povlsen, B Løfgren… - Journal of proteome …, 2018 - ACS Publications
… metabolic pathways in the Zucker diabetic fatty rat heart as T2DM develops using MS based
proteomics. The prediabetic state only induced minor pathway changes, whereas onset and …

Diabetes-induced proteome changes throughout development

D Johar, SM Ahmed, S El Hayek… - … Metabolic & Immune …, 2019 - ingentaconnect.com
changes of pregnancy combined with β-cell overload. This review discusses the molecular
basis of the biomolecular changes … Conclusion: Studying proteome changes in diabetes can …

Pathobiochemical changes in diabetic skeletal muscle as revealed by mass‐spectrometry‐based proteomics

K Ohlendieck - Journal of Nutrition and Metabolism, 2012 - Wiley Online Library
… The gel electrophoresis-based proteomic survey of normal versus nonobese diabetic rats
showed an altered expression profile for muscle-associated proteins that are involved in …

Characterization of proteomic changes in cardiac mitochondria in streptozotocin‐diabetic rats using iTRAQ™ isobaric tags

M Jüllig, AJ Hickey, MJ Middleditch… - PROTEOMICS …, 2007 - Wiley Online Library
changes at the proteomic level remains unclear. Here we report on proteomic changes in
diabetic rat heart mitochondria following 120 days of streptozotocin-diabetes using the recently …