A proteomic approach for understanding the mechanisms of delayed corneal wound healing in diabetic keratopathy using diabetic model rat

T Yamamoto, H Otake, N Hiramatsu… - International journal of …, 2018 - mdpi.com
… As we reported previously, changes in protein expression levels in the … of diabetic keratopathy.
In the present study, we performed a shotgun proteomic analysis of the cornea of STZ rats

Identification by a differential proteomic approach of the induced stress and redox proteins by resveratrol in the normal and diabetic rat heart

DHW Dekkers, K Bezstarosti… - Journal of Cellular …, 2008 - Wiley Online Library
… Our immunoblotting results demonstrate that resveratrol reversed the diabetes-induced
changes in stress protein expression except for catalase, which was further induced. …

Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPARα in the associated hypertrophy

S Ares-Carrasco, B Picatoste, E Camafeita… - … of Proteomics, 2012 - Elsevier
… pattern, samples from DM1, SHR, SHR/DM1 and control rats were analysed using proteomic
approaches (DIGE analysis; n = 6, each group). Then, to predict related cellular pathways, …

Proteomic study of serum proteins in a type 2 diabetes mellitus rat model by Chinese traditional medicine Tianqi Jiangtang Capsule administration

SX Zhang, H Sun, WJ Sun, GZ Jiao, XJ Wang - Journal of Pharmaceutical …, 2010 - Elsevier
Proteomics technology was for the first time applied to investigate the changes of serum proteins
levels in type 2 diabetes … complete proteome of organs and tissues in proteomics studies…

Proteomics and diabetic nephropathy

ML Merchant, JB Klein - Current Diabetes Reports, 2005 - Springer
… regard to protein expressional changes. These selective studies herein are referred to as
“targeted … mitochondrial proteins from diabetic rat kidney is associated with excess superoxide …

The application of post-translational modification oriented serum proteomics to assess experimental diabetes with complications

HM Chen, LC Lee, KY Hu, WJ Tsai, C Huang, HJ Tsay… - PloS one, 2018 - journals.plos.org
… To evaluate changes in glucose tolerance between the healthy control (n = 8) and the T2D
rats (n = 8), the rats were fasted overnight and a glucose solution was injected (1 g glucose/…

Differential expression of proteins in kidney, eye, aorta, and serum of diabetic and non‐diabetic rats

WC Cho, TT Yip, WS Chung, AW Leung… - Journal of cellular …, 2006 - Wiley Online Library
… findings of redox changes in the eye and aorta of diabetic rats, as well as … diabetic rats
compared with normal control rats. b: Principal components analysis of proteome data of diabetic

Proteome analysis of interleukin-1β–induced changes in protein expression in rat islets of Langerhans

PM Larsen, SJ Fey, MR Larsen, A Nawrocki… - Diabetes, 2001 - Am Diabetes Assoc
change in expression level of that protein) were picked up in the present study. Some of the
changes detected could also be due to changes in … protein expression changes were studied …

Proteome analysis of differential protein expression in brain of rats with type 1 diabetes mellitus

X Li, W Pan, GZ Yang, YN Di, F Zhao… - … & diabetes, 2011 - thieme-connect.com
Proteomic approach was applied to identify differential protein expressed in brain of rats with
type 1 diabetes … These can give some clues for the study of brain tissue changes in diabetes

[HTML][HTML] Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy

T Fugmann, B Borgia, C Révész, M Godo… - Kidney international, 2011 - Elsevier
… The results of this study show that in vivo biotinylation facilitates the detection of disease-specific
changes in the abundance of accessible proteins in rat kidneys after STZ-induced …