… rats but that this upregulation was blunted in diabetic animals. Nevertheless, when we treated
the wounded skin of diabetic rats with topical insulin … in the insulin signaling pathways (…

… sensitivity in skin tissue with that in liver tissue, and also observed the regulation of insulin
… insulin receptor, phos-AKT, IGF-1 in type II diabetic rat skin compared with that in normal rat …

… provided better rates of wound healing than treatment with base or control preparations,
5 and one in which diabetic rats that received topical insulin alone or in combination with …

… factor (TNF)-α, (B) interleukin (IL)-1β, and (C) IL-6, and levels of the anti-inflammatory
cytokine (D) IL-10 in burn wounds of diabetic rats treated with either topical insulin cream insulin …

… the regulation of the insulin signaling pathway in wound healing and skin repair of normal
and diabetic rats, and, in parallel, the effect of a topical insulin cream on wound healing and …

… However, the hyposensitivity of the cornea in diabetic rats was restored to normal by insulin
exposure. This change in corneal sensitivity suggests that the hyposensitivity observed in …

… the effects of topical insulin administration on burn wound … topical insulin application to
partial thickness burn wounds accelerates wound healing in rats with or without acute diabetes. …

… The results of this investigation, obtained on alert, conscious, in-bred chronic diabetic rats,
indicate that these methods of enhanced transdermal insulin delivery can provide consistent, …

… in control and diabetic rats; the results showed that insulin cream increases inflammatory
cell infiltration, and collagen deposition in diabetic rats, whereas non-diabetic rats show no …

… Articles were limited to journal articles with the keywords “topical insulin”, diabetes, and …
diabetic rats without TI. This study also compared 1, 2, or 5 U insulin in healthy and diabetic rats…