… Our results suggest that NLRP3 inflammasome activation can be associated especially with
the pathogenesis of PDR. The lack of differences in TNF-α, IL-6, and IFN-γ also alludes that …

… of the NLRP3 Inflammasome. Though direct inhibition of the NLRP3 Inflammasome is …
hopeful that local inhibition of the NLRP3 Inflammasome may reduce the disease burden of …

… NLRP3 inflammasome components in the PBMCs of patients with DR. Our data indicated that
key NLRP3 inflammasome … , and activation of NLRP3 inflammasomes triggers an increase …

… Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory
and angiogenic pathways. In this study, we evaluated NLRP3 inflammasome in a double …

… In the diabetic eye, the NLRP3 inflammasome is activated by several … NLRP3 inflammasome
and pyroptosis leading to DR. The present research highlighted some inhibitors of NLRP3/…

… Involvement of the NLRP3 inflammasome in DR has been established previously and in …
was to characterize activation of the NLRP3 inflammasome leading to DR onset using donor …

… of diabetic retinopathy [10]. Based on these findings, we favor a model of ROS that activate
the NLRP3 inflammasome … and TXNIP, contributing to the progression of diabetic retinopathy. …

… NLRP3 inflammasome pathway. (a) Western blot analysis of proteins in the NLRP3 inflammasome
… HG + VD, and NG + NLRP3-overexpressing and HG + NLRP3-knockdown groups. (b) …

… NLRP3 inflammasome may be involved in retinal disease. … cell death by regulating the
NLRP3 inflammasome (19). … using primary human retinal microvascular endothelial cells (…

… , an inhibitor of the NLRP3 inflammasome, on diabetic retinopathy (DR) mice. The general
physiological condition of each group of mice was recorded. Retinal blood vessels were …