Osteogenesis imperfecta (OI) is a genetic bone fragility disorder characterized by low bone
mass, skeletal deformity, and variable short stature. OI is predominantly caused by dominant …

Osteogenesis imperfecta (OI) is the most prevalent heritable bone fragility disorder in
children. It has been known for three decades that the majority of individuals with OI have …

… imperfecta, … Diagnosis of osteogenesis imperfecta may be done prenatally (in severe
cases), clinically, radiographically, or via biochemical or genetic examination. Medical treatment …

Osteogenesis imperfecta (OI) is an inheritable disorder characterized by bone fragility with
various symptoms of connective tissue disorders. OI is commonly classified by Sillence's …

Osteogenesis imperfecta (OI) is a heritable bone dysplasia characterized by bone fragility and
long bone deformities. Approximately 85% of OI cases are caused by dominant autosomal …

… Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders of connective
tissue characterised by bone fragility and other evidence of connective tissue malfunction.[1] …

… , medical treatment and orthopaedic surgery as necessary. Medical treatment consists of …
are widely used in the treatment of moderate to severe osteogenesis imperfecta, from infancy to …

… Osteogenesis imperfecta (OI) is the collective term for a heterogeneous group of connective
tissue syndromes characterized primarily by liability to fractures throughout life. Since the …

… Osteogenesis imperfecta (OI) is a rare disorder of type 1 collagen with 13 currently
identified types attributable to inherited abnormalities in type 1 collagen amount, structure, or …

… form of the disorder will advance clinical diagnosis and potentially stimulate targeted …
diagnosis, management, and treatment, we describe the defects causing osteogenesis imperfecta …