… The diagnosis is mainly clinical and must be distinguished from other skeletal abnormalities
and child abuse. The treatment is multidisciplinary, and it is aimed to improve the quality of …

Publisher Summary Osteogenesis imperfecta (OI) or “brittle bone disease” is characterized
by reduced skeletal mass and bone fragility. OI has served as the paradigm for heritable …

Introduction: Osteogenesis imperfecta (OI) is a heritable disease characterized by bone
fragility. A wide range of clinical severity and heterogeneity of the molecular defects is reported. …

… density in osteogenesis imperfecta … osteogenesis imperfecta patients, it is not diagnostic.
Assessment of bone mineral density is not clinically useful in managing osteogenesis imperfecta…

Osteogenesis imperfecta (OI) is a genetically determined disorder of connective tissue
characterized by bone fragility. The disease state encompasses a phenotypically and …

… Osteogenesis imperfecta (OI) is a heterogeneous rare connective tissue disorder commonly
… , classification, diagnostic methods, related to human concerned disease and treatment. The …

… The term osteogenesis imperfecta (OI) was originally used to describe a group of … In the
modern era of advanced genetic studies, the term osteogenesis imperfecta is used as an …

… Osteogenesis imperfecta (01) is a skeletal disorder of remarkable … Osteogenesis imperfecta:
rehabilitation approach with … Consequences of an osteogenesis imperfecta diagnosis for …

… for osteogenesis imperfecta as a collagen-related disorder. The more prevalent autosomal
dominant forms of osteogenesis imperfecta are … of dominant osteogenesis imperfecta include …

… Osteogenesis imperfecta (OI) is a rare clinically and genetically heterogeneous systemic
disorder of bone and connective tissue characterized by bone fragility and physical findings …