… Bisphosphonates in Osteogenesis Imperfecta Bisphosphonates are the most widely used
agents for the treatment of osteogenesis imperfecta. In the present review, I will review the …

… COL1A2), whereas recessive osteogenesis imperfecta is caused by mutations … diagnostic
aspects are discussed, as are current and potential drug regimens and cell therapy treatments…

… Growth hormone treatment in osteogenesis imperfecta with … five years of treatment of severe
osteogenesis imperfecta. Acta … Clinical signs and diagnosis of osteogenesis imperfecta in …

… of bone resorptionand are widely used to treat children and adults with osteogenesis
imperfecta. Bisphosphonates tried clinically in the treatment of OI are pamidronate, zoledronate, …

… Fractures are the main characteristic in patients with osteogenesis imperfecta (OI), also
called “brittle bone disease”. OI is a genetic disorder with a disturbance of the production and …

… , for the most part, a clinical diagnosis with investigations usually having a role in guiding
or monitoring treatment rather than in establishing the diagnosis. Management, at least of …

… imperfecta. It is important to know how to identify these characteristics in order to … the
diagnosis, optimize the treatment, and differentiate osteogenesis imperfecta from other …

… Sillence'" has established a classification of osteogenesis imperfecta that is related to …
treatment or prognosis. We continue to use the functional classification of osteogenesis imperfecta …

… Osteogenesis imperfecta (OI) is an inherited skeletal dysplasia characterized by bone
fragility and skeletal deformities. While the majority of cases are associated with pathogenic …

… Osteogenesis imperfecta subjects not diagnosed with DI may still present with abnormal
dental development that may weaken their structure. Short root and slender shape, abnormal …