Diagnostic instability and reversals of chronic obstructive pulmonary disease diagnosis in individuals with mild to moderate airflow obstruction

SD Aaron, WC Tan, J Bourbeau, DD Sin… - American journal of …, 2017 - atsjournals.org
airflow obstruction at baseline would be unlikely to show diagnostic instability or diagnostic
… decline in frequency as the FEV 1 /FVC ratio falls further below the diagnostic threshold. …

Pathology of chronic airflow obstruction

WM Thurlbeck - Chest, 1990 - Elsevier
… are major factors in severe obstruction. Lesser degrees of emphysema may be … airflow
obstruction. Emphysema, the dominant lesion in patients with severe chronic airflow obstruction, …

Some clinical problems in patients with airways obstruction

DMM Tumer-Warwick - Chest, 1982 - journal.chestnet.org
… basis of wheeziness and airflow obstruction, the term asthma … , to consider the diagnostic
errors which frequently arise, and … at least two distinct patterns of instability-the morning dipper, …

Diagnostic accuracy of capnovolumetry for the identification of airway obstruction–results of a diagnostic study in ambulatory care

C Kellerer, N Jankrift, RA Jörres, K Klütsch… - Respiratory …, 2019 - Springer
diagnostic accuracy of ultrasound-based capnovolumetry for the identification of airway
obstruction… were included in the diagnostic study. As reference standard, the presence of airway …

COPD overdiagnosis in primary care: a UK observational study of consistency of airflow obstruction

L Josephs, D Culliford, M Johnson… - NPJ primary care …, 2019 - nature.com
… Chronic obstructive pulmonary disease (COPD) is heterogeneous, but … airflow obstruction
(AFO) is fundamental to diagnosis. We studied AFO consistency from initial diagnosis and …

Simultaneous assessment of airway instability and respiratory dynamics with low-dose 4D-CT in chronic obstructive pulmonary disease: a technical note

MO Wielpütz, R Eberhardt, M Puderbach… - Respiration, 2014 - karger.com
… may be due to insufficiently standardized diagnostic tools. Endoscopic techniques are possibly
… as having an equal diagnostic impact as bronchoscopy for tracheal instability, and should …

Airflow pattern complexity and airway obstruction in asthma

J Veiga, AJ Lopes, JM Jansen… - Journal of applied …, 2011 - journals.physiology.org
obstruction in the complexity of airflow patterns, and 2) to evaluate the clinical potential of
the ApEnQ in the diagnosis … ) and is prone to instabilities and exacerbations, whereas higher …

Obstruction phenotype as a predictor of asthma severity and instability in children

RL Sorkness, EM Zoratti, M Kattan, PJ Gergen… - Journal of Allergy and …, 2018 - Elsevier
… However, a 10% change in FEV 1 with bronchodilation in children has diagnostic specificity
for asthma 15 and an association with asthma instability 16 in children. Because FEV 1 …

Instability in the COPD diagnosis upon repeat testing vary with the definition of COPD

R Perez-Padilla, FC Wehrmeister, M Montes de Oca… - PLoS …, 2015 - journals.plos.org
… Using FEV 1 /FEV 6 <LLN or GOLD stage 2-4 as the criterion for airflow obstruction reduces
inconsistencies in the diagnosis of mild COPD. Further improvement could be obtained by …

Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD

RA O'donnell, C Peebles, JA Ward, A Daraker… - Thorax, 2004 - thorax.bmj.com
… higher in smokers with airflow obstruction than in healthy … be affected by peripheral airways
obstruction, 14 displayed a … has limitations; peripheral airway instability and loss of elastic …