[HTML][HTML] Suggestions for designing studies investigating diagnostic accuracy of biomarkers

M Zhang, ZD Hu - Annals of Translational Medicine, 2019 - ncbi.nlm.nih.gov
… The number of diagnostic test accuracy (DTA) studies concerning biomarkers have
gradually increased during the past years. However, study designs remain imperfect, and the …

Diagnostic test accuracy of novel biomarkers for lupus nephritis—An overview of systematic reviews

JAR Guimarães, SC Furtado, ACS Lucas, B Mori… - PLoS …, 2022 - journals.plos.org
… is the accuracy of the new serum and urinary biomarkers studied for the diagnosis of LN
in … studies evaluating the diagnostic accuracy of new serum or urinary biomarkers of lupus …

… the diagnostic accuracy of five common tumour biomarkers and CA19-9 for pancreatic cancer: a protocol for a network meta-analysis of diagnostic test accuracy

L Ge, B Pan, F Song, J Ma, D Zeraatkar, J Zhou… - BMJ open, 2017 - bmjopen.bmj.com
… We will conduct a network meta-analysis of diagnostic test accuracy. We have registered
the protocol on the international prospective register of systematic review (PROSPERO).27 We …

Flexible combination of multiple diagnostic biomarkers to improve diagnostic accuracy

T Xu, Y Fang, A Rong, J Wang - BMC medical research methodology, 2015 - Springer
biomarkers to improve the accuracy of diagnostic tests. Combining the measurements of these
biomarkersaccuracy of the resultant diagnostic test is usually improved. To measure the …

Comparison of diagnostic accuracy of biomarkers with pooled assessments

A Liu, EF Schisterman - Biometrical Journal: Journal of …, 2003 - Wiley Online Library
… The purpose of this paper is to illustrate a statistical testing procedure for comparing biomarkers
in … of two biomarkers, and propose a statistical test to compare biomarkers of interest. An …

From accuracy to patient outcome and cost-effectiveness evaluations of diagnostic tests and biomarkers: an exemplary modelling study

H Koffijberg, B van Zaane, KGM Moons - BMC medical research …, 2013 - Springer
… The number of diagnostics tests and (bio)… diagnostic tests and markers, the potential negative
health consequences due to over testing, and the steeply rising costs for diagnostic testing […

Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis

EM Balk, JPA Ioannidis, D Salem, PW Chew… - Annals of emergency …, 2001 - Elsevier
… aimed to characterize the test performance of these biomarkers to diagnose ACI, both …
diagnostic performance of biomarker tests, we also included studies that assessed AMI diagnosis

Biomarkers: potential uses and limitations

R Mayeux - NeuroRx, 2004 - Springer
… No matter how high the odds ratio or relative risk, a biomarker of this type could not be
expected to function as a diagnostic test unless it is a manifestation of the disease. For example, …

Guidance for studies evaluating the accuracy of biomarker-based nonsputum tests to diagnose tuberculosis

PK Drain, J Gardiner, H Hannah… - The Journal of …, 2019 - academic.oup.com
… We provide guidance on the design of diagnostic accuracy studies evaluating nonsputum,
biomarker-based tests within the context of WHO’s target product profile for such tests. Study …

From biomarkers to medical tests: the changing landscape of test evaluation

AR Horvath, SJ Lord, A StJohn, S Sandberg… - Clinica chimica acta, 2014 - Elsevier
… the new diagnostic test will be used as a ‘replacement’ test, … the diagnostic accuracy of the
new test versus the existing test … ’ test we need information to compare the diagnostic accuracy