Zn II and Hg II binding to a designed peptide that accommodates different coordination geometries

D Szunyogh, B Gyurcsik, FH Larsen, M Stachura… - Dalton …, 2015 - pubs.rsc.org
… to design a peptide with a broader metal ion binding profile. In a biotechnological perspective,
overexpression of such a peptidepeptide in terms of the metal site coordination geometry

Harnessing natures ability to control metal ion coordination geometry using de novo designed peptides

AFA Peacock, O Iranzo, VL Pecoraro - Dalton Transactions, 2009 - pubs.rsc.org
Peptide sequences capable of binding two equivalents of the same metal ion in separate
sites with different coordination geometries more closely approaches our goal of preparing …

Peptide-coordination self-assembly for the precise design of theranostic nanodrugs

M Cao, R Xing, R Chang, Y Wang, X Yan - Coordination Chemistry …, 2019 - Elsevier
… the significant impact of metal coordination chemistry on directing peptide self-assembly to …
different coordination geometries and stoichiometries to trigger the self-assembly of a peptide-…

Design of Stable β‐sheet‐based cyclic peptide assemblies assisted by metal coordination: selective homo‐and heterodimer formation

M Panciera, M Amorín, L Castedo… - Chemistry–A European …, 2013 - Wiley Online Library
… combination of the linear coordination geometry, the linearity … the metal would be coordinated
to two different ligands, such … coordination it would be necessary to use the cyclic peptide

Peptide-Coordination Self-Assembly: Supramolecular Design and Biomedical Applications

J Zhang, R Chang, S Li, R Xing, Q Zou - Colloids and Surfaces A …, 2024 - Elsevier
… ions have different coordination geometries. … different properties and characteristics. In this
section, we will review the important effects of various components of peptide-coordination self…

Controlling and fine tuning the physical properties of two identical metal coordination sites in de novo designed three stranded coiled coil peptides

O Iranzo, S Chakraborty, L Hemmingsen… - Journal of the …, 2011 - ACS Publications
… (II) with high affinity and different coordination geometries. Substitution of the Leu by Cys or
designed peptides capable of binding 2 equiv of Cd(II) with identical coordination geometries

[HTML][HTML] Heterochromia in designed metallopeptides: geometry-selective binding of CdII in a de novo peptide

O Iranzo, C Cabello, VL Pecoraro - … Chemie (International ed. in …, 2007 - ncbi.nlm.nih.gov
… In conclusion, we are able to design a single, short peptide (Grand L16PenL26AL30C) …
pseudotetrahedral and the other with a trigonal planar coordination geometry. More interestingly, …

Tunable helicity, stability and DNA-binding properties of short peptides with hybrid metal coordination motifs

SJ Smith, RJ Radford, RH Subramanian… - Chemical …, 2016 - pubs.rsc.org
… One route toward this goal has been the design of entirely … Another route is to design natural
peptides with a propensity to … metal coordination geometry and the structure of the peptide. …

Peptide architecture. Design of stable. alpha.-helical metallopeptides via a novel exchange-inert ruthenium (III) complex

MR Ghadiri, AK Fernholz - Journal of the American Chemical …, 1990 - ACS Publications
… plane defined by P(3)-WP(4), such that the overall coordination geometry is dodecahedral.
… On the other hand, the histidine signals in the Ru(III)-peptide complex display paramagnetic …

Copper binding to the amyloid-β (Aβ) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Aβ-(1 …

CD Syme, RC Nadal, SEJ Rigby, JH Viles - Journal of Biological Chemistry, 2004 - ASBMB
… is growing, and our studies have made a significant contribution to understanding the mode
… representing various fragments of the amyloid-β peptide were synthesized by employing …