Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis

M Economou, TA Trikalinos, KT Loizou… - Official journal of the …, 2004 - journals.lww.com
… Carriage of the three NOD2 variants and susceptibility to Crohn's disease. Each study is
represented by an estimate for the genetic effect of the NOD2 variants, as conveyed by the odds …

Differential effect of genetic burden on disease phenotypes in Crohn's disease and ulcerative colitis: analysis of a North American cohort

AN Ananthakrishnan, H Huang… - Official journal of the …, 2014 - journals.lww.com
… paradigms for management of Crohn's disease (CD) and ulcerative … effects of genetics on
disease behavior across CD and UC, suggesting differential contribution of genetics to disease

Opposing effects of smoking in ulcerative colitis and Crohn's disease may be explained by differential effects on dendritic cells

A Ueno, H Jijon, S Traves, R Chan… - … bowel diseases, 2014 - academic.oup.com
… The mechanisms underlying the differential effects of cigarette smoking in patients with
Crohn's disease (CD) and ulcerative colitis (UC) remain unknown. Smoking has been …

[HTML][HTML] Differential effect of vitamin D on NOD2-and TLR-induced cytokines in Crohn's disease

S Dionne, MR Calderon, JH White, B Memari… - Mucosal …, 2014 - Elsevier
Accumulating evidence implicates defective innate immunity in the pathogenesis of Crohn's
disease (CD). Ineffectual NOD2 (nucleotide-binding oligomerization domain 2) is the most …

Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis

LM Diaz-Gallo, L Espino-Paisán… - … bowel diseases, 2011 - academic.oup.com
… Our results indicate that there is a differential association of the R263Q and R620W
polymorphisms with IBD. On the one hand, the PTPN22 263Q loss-of-function variant is a protective …

Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease

GP Christophi, R Rong, PG Holtzapple… - … bowel diseases, 2012 - academic.oup.com
… bowel disease (IBD) is a chronic immune-mediated disease … variants of IBD are ulcerative
colitis (UC) and Crohn's disease (CD)… The current working model of IBD pathogenesis posits a …

Consistent across-tissue signatures of differential gene expression in Crohn's disease

AL Hughes - Immunogenetics, 2005 - Springer
… with significant differential expression across ileum and colon in inflammatory bowel disease
(IBD). Statistically significant differences in expression levels between Crohn's disease (CD…

Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis

CR Mantyh, SR Vigna, RR Bollinger, PW Mantyh… - Gastroenterology, 1995 - Elsevier
… may potentially ameliorate the proinflammatory effects of SP in IBD and other inflammatory
… indicate a subclinical disease state. In conclusion, we have shown the differential distribution …

[HTML][HTML] Effect of fish oil enriched enteral diet on inflammatory bowel disease tissues in organ culture: differential effects on ulcerative colitis and Crohn's disease

D Meister, S Ghosh - World journal of gastroenterology, 2005 - ncbi.nlm.nih.gov
AIM: To investigate the influence of fish oil enriched enteral diet on intestinal tissues taken
from Crohn’s disease (CD), ulcerative colitis (UC) and non-inflamed non-IBD control patients …

Crohn's disease

F Shanahan - The Lancet, 2002 - thelancet.com
… and some separately linked to one disease or the other. Thus, … disease type, but relatives
of patients with Crohn's disease have an increased risk of ulcerative colitis and Crohn's disease