Impact of regulatory variation across human iPSCs and differentiated cells
… Interestingly, we find the increased variation in differentiated cell types is also associated …
genes (Supplemental Materials), further highlighting the level of regulatory control in iPSCs. …
genes (Supplemental Materials), further highlighting the level of regulatory control in iPSCs. …
Generation of iPSCs from cultured human malignant cells
… other human cancer cells can be reprogrammed into iPSCs. Interestingly, the oncogenic
mutations present in the reprogrammed KBM7-iPSCs do not fully prevent cellular differentiation …
mutations present in the reprogrammed KBM7-iPSCs do not fully prevent cellular differentiation …
Differentiation of human iPSCs into functional podocytes
C Rauch, E Feifel, G Kern, C Murphy, F Meier… - PloS one, 2018 - journals.plos.org
… method to generate podocyte-like cells from human iPSCs. This represents a minimal invasive
and ethically accepted way to obtain human podocytes in appropriate quantities for basic …
and ethically accepted way to obtain human podocytes in appropriate quantities for basic …
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs
… human iPSCs and SCNT-ESC derivatives. We provide proof-of-concept that differentiated
cells derived from human iPSCs are … We conclude that human iPSCs are capable of replacing …
cells derived from human iPSCs are … We conclude that human iPSCs are capable of replacing …
[HTML][HTML] Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies
… to assess the differentiation status and functionality of three human cell types (hiPSCs, …
usefulness in human cell therapy. Functionality and differentiation of these three cell types were …
usefulness in human cell therapy. Functionality and differentiation of these three cell types were …
Differentiation of human induced pluripotent stem cells into erythroid cells
M Ebrahimi, M Forouzesh, S Raoufi, M Ramazii… - Stem Cell Research & …, 2020 - Springer
… of HSCs from human iPSCs. Many studies have aimed to differentiate human iPSCs into
RBCs … In general, there are three steps for differentiation of iPSCs into RBCs, including the …
RBCs … In general, there are three steps for differentiation of iPSCs into RBCs, including the …
Robust detection of undifferentiated iPSC among differentiated cells
K Sekine, S Tsuzuki, R Yasui, T Kobayashi, K Ikeda… - Scientific reports, 2020 - nature.com
… whether undifferentiated iPSCs were present in the differentiated cells in the … differentiated
cells and cultivated them for ~1 week in iPSC maintenance state to derive undifferentiated cell …
cells and cultivated them for ~1 week in iPSC maintenance state to derive undifferentiated cell …
Improved approach for chondrogenic differentiation of human induced pluripotent stem cells
… differentiation, our approach involves direct induction of human mesenchymal stem/stromal
cells … -derived chondrogenic differentiated cell pellets after 3 weeks of differentiation (3 knees…
cells … -derived chondrogenic differentiated cell pellets after 3 weeks of differentiation (3 knees…
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
BY Hu, JP Weick, J Yu, LX Ma… - Proceedings of the …, 2010 - National Acad Sciences
… improved differentiation. Here, we compared the neural-differentiation potential of human
iPSCs, … We found that human iPSCs differentiate to neuroepithelial (NE) cells and functional …
iPSCs, … We found that human iPSCs differentiate to neuroepithelial (NE) cells and functional …
Efficient differentiation of human iPSC‐derived mesenchymal stem cells to chondroprogenitor cells
RM Guzzo, J Gibson, RH Xu, FY Lee… - Journal of cellular …, 2013 - Wiley Online Library
… vitro conditions for efficient differentiation to the chondrocytic … progenitor cell population from
differentiating human iPSCs and … of iPSCs and limiting the heterogeneity of the differentiated …
differentiating human iPSCs and … of iPSCs and limiting the heterogeneity of the differentiated …
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