… of the antigen-specific signal delivered through the T-cell receptor (TCR) or the role of non-…
driving differentiation of effector and memory T cells. The ability of any individual naive T cell …

… in terms of their ability to populate the memory T cell pool. Over the past decade, the signalling
… and other environmental cues — influence CD8 + T cell transcription, metabolism and …

… arise early when peripheral tissues are seeded from the pool of recently activated T cells …
is a key priority, as these cells are exposed to unique metabolic cues, nutrient and O 2 levels …

… memory T-cell pool [50], which indicates that memory cells … developmental cues are interpreted
by a developing T cell to … of innate signaling pathways in memory T cells is minimal, it is …

… We integrate T RM into a ‘terrace’ model that classifies memory T cells along a continuous
… a stable pool of memory T cells that patrol the body for reinfection. Such memory T cells are …

… fully understand the nature of the CD4 + memory T-cell pool. … marker expression and
cytokine cues driving T RM formation; … to differentiate between memory T H 1 and T FH memory …

… By contrast, MPECs can differentiate into memory T cells that survive long term and provide
… pool (which we will refer to as single cell asymmetry), or whether the population response …

… homogeneous effector subsets and others differentiating toward mixed effector populations.
… CD8 + T cell subpopulations. Unlike naive CD8 + T cells, memory T cells differentiated …

… the differentiation and maintenance of CD8 + memory T cells … of the memory T cell pool
contains, the cues that influence their … to create the most useful memory T cell pool by vaccination. …

… Cell-intrinsic differentiation cues, in particular those dependent on … of some effector T
cell clones but not others within the memory T cell pool and suggest a role for TCR signals in …