Ellagic acid prevents rat colon carcinogenesis induced by 1, 2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway

S Umesalma, G Sudhandiran - European journal of pharmacology, 2011 - Elsevier
Ellagic acid (EA) a major component of berries possesses … of ellagic acid in fostering
apoptosis in 1,2-dimethyl hydrazine (… rats, group II—rats received ellagic acid (60 mg/kg body …

Antiproliferative and apoptotic-inducing potential of ellagic acid against 1, 2-dimethyl hydrazine-induced colon tumorigenesis in Wistar rats

S Umesalma, P Nagendraprabhu… - Molecular and cellular …, 2014 - Springer
Ellagic acid (EA), a major component of polyphenol possesses attractive remedial features.
The aim of this study is to divulge the potential effect of EA during 1,2-dimethyl hydrazine (…

Chemomodulation of the antioxidative enzymes and peroxidative damage in the colon of 1, 2‐dimethyl hydrazine‐induced rats by ellagicacid

S Umesalma, G Sudhandiran - Phytotherapy Research, 2010 - Wiley Online Library
… Toward this goal, a chemopreventive study was conducted to evaluate the potential effect
of ellagic acid (EA) against 1,2-dimethylhydrazine (DMH-) induced colon carcinogenesis in …

… inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF‐κB, iNOS, COX‐2, TNF‐α, and IL‐6 in 1, 2‐dimethylhydrazine‐induced rat colon …

S Umesalma, G Sudhandiran - Basic & clinical pharmacology & …, 2010 - Wiley Online Library
… action of ellagic acid, the present study was focused to determine the ability of ellagic acid in
… NF-κB, iNOS, COX-2, TNF-α and IL-6 against 1,2-dimethylhydrazine-induced colon cancer. …

Ellagic acid modulates antioxidant status, ornithine decarboxylase expression, and aberrant crypt foci progression in 1, 2-dimethylhydrazine-instigated colon …

KN Kumar, SB Raja, N Vidhya… - Journal of agricultural …, 2012 - ACS Publications
… This study exemplifies the chemopreventive efficacy of ellagic acid (EA) in 1,2-dimethylhydrazine
(DMH) initiated CRC in rats. Subcutaneous injection of DMH (40 mg/kg body weight …

Beneficial influence of ellagic acid on biochemical indexes associated with experimentally induced colon carcinogenesis

U Syed, S Ganapasam - Journal of Cancer Research and …, 2017 - journals.lww.com
… Graph represents the effect of ellagic acid on the levels of lysosomal hydrolases in the
colon of control and experimental groups of rats. Activity is expressed as μmol of p-nitrophenol …

Electrochemical immobilization of ellagic acid phytochemical on MWCNT modified glassy carbon electrode surface and its efficient hydrazine electrocatalytic activity in …

AS Kumar, R Shanmugam, N Vishnu, KC Pillai… - Journal of …, 2016 - Elsevier
Ellagic acid (EA) is a lactone and polyphenolic functional groups-containing phyto-chemical …
Finally, amperometric it and flow injection analysis for highly selective sensing of hydrazine

[HTML][HTML] Ellagic acid modulates cisplatin toxicity in DMH induced colorectal cancer: Studies on membrane alterations

Y Goyal, A Koul, P Ranawat - Biochemistry and Biophysics Reports, 2022 - Elsevier
… The present study, therefore, explores the role of Ellagic acid in modulating the topography
and lipid dynamics of the colonic membranes after CP exposure in DMH-induced colorectal …

Ellagic acid: an unusually versatile protector against oxidative stress

A Galano, M Francisco Marquez… - Chemical research in …, 2014 - ACS Publications
… • NO 2 radicals with ellagic acid and its methyl and dimethyl derivatives in gas phase and in
aqueous solution. They found that the efficiency of ellagic acid and its derivative to scavenge …

Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model

K Akagi, M Hirose, T Hoshiya, Y Mizoguchi, N Ito… - Cancer letters, 1995 - Elsevier
… In the present study, ellagic acid and quercetin clearly inhibited small intestinal carcinogenesis
when given either during or after DMBDD treatment, the effect being more pronounced in …