A metabolomic study of the urine of rats with Alzheimer's disease and the efficacy of Ding‐Zhi‐Xiao‐Wan on the afflicted rats
Y He, Y Wang, S Liu, Z Pi, Z Liu… - Journal of separation …, 2020 - Wiley Online Library
… Ding-Zhi-Xiao-Wan has long been used for the routine treatment of Alzheimer's disease.
However, the mechanism of Ding-Zhi-Xiao-Wan … mechanism of Ding-Zhi-Xiao-Wan on …
However, the mechanism of Ding-Zhi-Xiao-Wan … mechanism of Ding-Zhi-Xiao-Wan on …
Study on the compatibility interactions of formula Ding-Zhi-Xiao-Wan based on their main components transport characteristics across Caco-2 monolayers model
Y Zheng, G Feng, Y Sun, S Liu, Z Pi, F Song… - Journal of Pharmaceutical …, 2018 - Elsevier
… In this study, the compatibility mechanism of Ding-Zhi-Xiao-Wan (DZXW) was investigated
by using the in vitro Caco-2 cell monolayers model. Decomposing the formula into single herb …
by using the in vitro Caco-2 cell monolayers model. Decomposing the formula into single herb …
A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic …
XZ Dong, ZL Li, XL Zheng, LH Mu, G Zhang… - Journal of …, 2013 - Elsevier
… Ding-Zhi-Xiao-Wan (DZ) is a famous formula which was originally recorded in Chinese …
“Ding-Zhi” means ameliorate or cure or recovery the moodiness, forgetfulness, learning and …
“Ding-Zhi” means ameliorate or cure or recovery the moodiness, forgetfulness, learning and …
Comparative pharmacokinetics of Ding‐Zhi‐Xiao‐Wan preparation and its single herbs in rats by using a putative multiple‐reaction monitoring UPLC‐MS/MS method
Y Sun, Y He, S Liu, H Gao, Z Pi, F Song… - Phytochemical …, 2021 - Wiley Online Library
Introduction The formula of Chinese medicine, Ding‐Zhi‐Xiao‐Wan (DZXW), has the distinct
feature of compatibility therapy, which is attributed to the interactions of multi‐herbs. …
feature of compatibility therapy, which is attributed to the interactions of multi‐herbs. …
UPLC-Q-TOF-MSE analysis of the constituents of Ding-Zhi-Xiao-Wan, a traditional Chinese antidepressant, in normal and depressive rats
L Xu, LH Mu, J Peng, WW Liu, X Tan, ZL Li… - … of Chromatography B, 2016 - Elsevier
Ding-Zhi-Xiao-Wan (DZXW) is a traditional Chinese medicine widely used for treating
depression. To clarify the bioactive constituents of DZXW, a new rapid ultra-performance liquid …
depression. To clarify the bioactive constituents of DZXW, a new rapid ultra-performance liquid …
Serum lipidomics study of Ding-Zhi-Xiao-Wan effect on Alzheimer's disease using online liquid extraction surface analysis coupled to direct infusion mass …
NN Zhao, YF Sun, L Zong, S Liu, FR Song… - International Journal of …, 2018 - Elsevier
Disorder of lipid metabolism is closely related to the incidence of Alzheimer's disease (AD).
Regulation of lipid disorder is one of the important mechanisms of drug therapy for AD. In this …
Regulation of lipid disorder is one of the important mechanisms of drug therapy for AD. In this …
Analysis and Identification of the Chemical Constituents of Ding‐Zhi‐Xiao‐Wan Prescription by HPLC‐IT‐MSn and HPLC‐Q‐TOF‐MS
S Tang, S Liu, Z Liu, F Song… - Chinese Journal of …, 2015 - Wiley Online Library
Ding‐Zhi‐Xiao‐Wan (DZXW) is a famous traditional Chinese medicine (TCM) formula, which
is composed of four herbs, Ginseng Radix, Poria, Polygala Radix and Acori Tatarinowii …
is composed of four herbs, Ginseng Radix, Poria, Polygala Radix and Acori Tatarinowii …
A target integration strategy for analyzing multidimensional chemical and metabolic substance groups of Ding-Zhi-Xiao-Wan prescription by using ultra-high …
G Feng, Z Liu, S Liu, J Xing, F Song, Z Pi - Journal of Chromatography A, 2019 - Elsevier
It is both challenging and meaningful for identifying the in vivo metabolites of the complex
prescription owning to more complex chemical constituents and better therapeutic effect than …
prescription owning to more complex chemical constituents and better therapeutic effect than …
The Therapeutic Effect and Potential Pharmacological Mechanisms of Ding-Zhi-Xiao-Wan on Depression were Investigated by Meta-analysis, Network Pharmacology …
LL Lin, HB Wu, ZK Qiu - Current Computer-Aided Drug Design, 2024 - ingentaconnect.com
Introduction: Ding-Zhi-Xiao-Wan (DZXW) produces potential antidepressant-like effects.
However, its antidepressant mechanisms are still unclear. Objective: To analyze the …
However, its antidepressant mechanisms are still unclear. Objective: To analyze the …
Effect of Dingzhi Xiaowan on miR-16 expression and 5-HT reuptake
WY Zhu, X Feng, J Wang, YP Lu… - … Zhong yao za zhi …, 2018 - europepmc.org
… This study is to investigate the effect of antidepressant medicine prescription Dingzhi Xiaowan
(DZ) on miR-16 expression levels in vitro and in vivo, and to explore the mechanism of DZ …
(DZ) on miR-16 expression levels in vitro and in vivo, and to explore the mechanism of DZ …