Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of xenobiotics.
Because the structural and amino acid homology among esterases of different classes, …

… i values for the compounds toward three mammalian CEs when using o-nitrophenyl acetate
… inhibitor of mammalian CEs. This was demonstrated to be correct with a K i value of 1 nM …

… Carboxylesterases (CE) are ubiquitous enzymes found in both human and animal tissues …
We have recently identified benzil is a potent inhibitor of mammalian CEs, and in this study, we …

… The primary aim of this study was to examine whether the human carboxylesterases hCE-1 …
metabolism using CEs from other mammalian species. The expression of hCE-1 and hCE-2 …

… are widely expressed in multiple mammalian tissues.Carboxylesterases (CES) are multifunctional
… They have shown that the diphenylethane-1,2dione chemotype (benzil) is an excellent …

… (1). CES catalyze the hydrolysis of several pesticides within mammalian species. CES are
… obtained with pyrethroids and recombinant carboxylesterase isoforms, examine interactions …

… Several phase I enzymes are expressed in mammalian liver … composed of both paraoxonases
and carboxylesterases (CEs). … human and other mammalian carboxylesterases. Biochem …

… Humans and small mammals demonstrate different levels of carboxylesterase expression. …
it appears as though through evolution, higher mammals (primates) have lost expression of …

… (diphenylethane-1,2-dione) as a potent selective inhibitor of CEs, we sought to evaluate the
inhibitory activity of related 1,2-… In mammals, they tend to be expressed in tissues likely to be …

… We have synthesized and assessed the ability of symmetrical fluorobenzoins and fluorobenzils
to inhibit mammalian carboxylesterases (CE). The majority of the latter were excellent …