Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of gliamediated inflammation

JY Wang, LL Wen, YN Huang… - Current …, 2006 - ingentaconnect.com
neurodegenerative diseases. The mechanistic basis of the neuroprotective activity of
antioxidants does not only rely on the general free radical trapping or antioxidant activity per se in …

Antioxidants as treatment for neurodegenerative disorders

B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
… A direct antioxidant neuroprotective role has likewise been demonstrated for oestrogen and
direct antioxidants will become part of the standard therapy of certain neurodegenerative

Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach

C Behl, B Moosmann - Free Radical Biology and Medicine, 2002 - Elsevier
… of direct antioxidant structures for neuroprotective antioxidant … to the family of direct antioxidants
are neuroprotectants in … concerning antioxidant therapy of neurodegenerative disorders …

Oxidative stress, antioxidants and neurodegenerative diseases

I Casetta, V Govoni, E Granieri - Current pharmaceutical design, 2005 - ingentaconnect.com
… , the clinical evidence that antioxidants agents may prevent or … clinical trials on antioxidant
neuroprotection in Parkinson’s … might have direct antioxidant and neuroprotective effects [154]…

Antioxidant protection: a promising therapeutic intervention in neurodegenerative disease

N Ghosh, R Ghosh, SC Mandal - Free Radical Research, 2011 - Taylor & Francis
… The Trx system plays a key role in cell function by limiting oxidative stress directly via
antioxidant … The neuroprotective effect of the potent antioxidant tBHQ against 2’CH3-MPTP-induced …

Neurodegeneration by oxidative stress: a review on prospective use of small molecules for neuroprotection

E Singh, G Devasahayam - Molecular Biology Reports, 2020 - Springer
… decreases oxidative stress and contribute to neuroprotection. This … neurodegenerative
disorders. The perspective of this review is to study antioxidants and their role in neuroprotection. …

Effects of natural antioxidants in neurodegenerative disease

SL Albarracin, B Stab, Z Casas, JJ Sutachan… - Nutritional …, 2012 - Taylor & Francis
… Citation46 In addition to the direct induction of OS, Aβs can also indirectly generate an …
Citation90 Natural antioxidants like polyphenols provide neuroprotective effects through a …

Polyphenols and neurodegenerative diseases: potential effects and mechanisms of neuroprotection

RA Arias-Sánchez, L Torner, B Fenton Navarro - Molecules, 2023 - mdpi.com
… Their direct use and dietary supplementation could act as an antioxidant and neuroprotective
therapy for treating NDs. In addition, natural products, including polyphenols, represent a …

Neuroprotective effect of antioxidants in the brain

KH Lee, M Cha, BH Lee - International journal of molecular sciences, 2020 - mdpi.com
antioxidants shown to have neuroprotective effects that limit neurodegenerative disease. …
Antioxidants act to directly scavenge oxidizing radicals and regenerate oxidized biomolecules …

Neuroprotection and antioxidants

M Lalkovičová, V Danielisová - Neural regeneration research, 2016 - journals.lww.com
Neuroprotective methods often target oxidative stress and excitotoxicity, which together
with other factors lead to neuronal death and aggravate neurodegeneration… a direct/antioxidant. …