… mature cell types. Directed differentiation systems are well developed for ectodermal
pathways that result in neural and glial cells and the mesendodermal pathway for cardiac muscle …

… stem cell differentiation. By translating principles of development to the directed differentiation
of PSCs, it is now possible to generate highly enriched populations of different cell types …

… cell expansion systems to address this limitation. Progress in biomaterial design has also
allowed directed differentiation of stem cells … the study of stem cell responses to topographical …

… directed differentiation of telencephalic precursors from mouse embryonic stem (ES) cells …
5 d of SFEB culture causes nearly selective neural differentiation in ES cells (∼90%). In the …

… The differentiation capacity of human embryonic stem cells (hESCs) holds great promise
for … to efficiently direct the differentiation of human embryonic stem cells into hepatic cells in …

… used to direct stem cells to a … stem (ES) cells to differentiate into spinal progenitor cells, and
subsequently into motor neurons, through a pathway recapitulating that used in vivo. ES cell-…

… during tenogenic differentiation 46 , were expressed at a low level … directed differentiation.
These data suggest that our directed differentiation protocol is specific for differentiation …

… Importantly, this method for directed differentiation is broadly applicable to other PSC lines,
as we were able to generate hindgut spheroids from both H1 and H9 human ES cell lines …

… Our study demonstrates an approach to model human biliary development and disease
through a directed differentiation protocol that efficiently generates functional cholangiocyte cells …

… Here we report the isolation, propagation and directed differentiation of NCS cells from
hES cells. Gene expression analysis confirmed a molecular profile compatible with NCS cell …