Discontinuation of inhaled corticosteroids in COPD and the risk reduction of pneumonia

S Suissa, J Coulombe, P Ernst - Chest, 2015 - Elsevier
… This nonsignificant 5% reduction in the risk of pneumonia (rate ratio [RR… risk reduction
associated with ICS withdrawal in COPD. In this article, we assess the effect of ICS discontinuation

The risk of asthma exacerbation after stopping low-dose inhaled corticosteroids: a systematic review and meta-analysis of randomized controlled trials

MA Rank, JB Hagan, MA Park, JC Podjasek… - Journal of allergy and …, 2013 - Elsevier
… We sought to estimate the risk of asthma exacerbation in patients who stop low-dose inhaled
corticosteroids (ICSs) compared with those who continue ICSs in randomized controlled …

Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive pulmonary disease: the COPE study

P van der Valk, E Monninkhof… - American journal of …, 2002 - atsjournals.org
… The aim of this double-blind single center study (the COPE study) was to investigate the
effect of discontinuation of the inhaled corticosteroid fluticasone propionate (FP) on …

[HTML][HTML] Withdrawal of inhaled corticosteroids versus continuation of triple therapy in patients with COPD in real life: observational comparative effectiveness study

H Magnussen, S Lucas, T Lapperre, JK Quint… - Respiratory …, 2021 - Springer
… This was an observational comparative effectiveness study aimed to evaluate the effect of
inhaled corticosteroid (ICS) cessation versus continuation of triple therapy in COPD patients. …

Benefits and risks of inhaled corticosteroids in chronic obstructive pulmonary disease

M Bonay, C Bancal, B Crestani - Drug safety, 2002 - Springer
… Recently a small prospective, randomised, placebo-controlled, crossover trial evaluated
the effect of inhaled corticosteroids withdrawal on lung function, exercise capacity, respiratory …

[HTML][HTML] A proposal for the withdrawal of inhaled corticosteroids in the clinical practice of chronic obstructive pulmonary disease

M Miravitlles, BG Cosío, A Arnedillo, M Calle… - Respiratory …, 2017 - Springer
… 3 years, with a 20% risk reduction over the first month [69]. Of note, patients … discontinued
fluticasone showed greater reductions in severe pneumonia risk than those who discontinued

Withdrawal of inhaled corticosteroids in COPD: a meta-analysis

L Calzetta, MG Matera, F Braido, M Contoli… - Pulmonary …, 2017 - Elsevier
withdrawal of inhaled corticosteroid (ICS) in chronic obstructive pulmonary disease (COPD).
We performed a quantitative synthesis in order to assess real impact of ICS discontinuation

The risk/benefit of inhaled corticosteroids in chronic obstructive pulmonary disease

M Bonay, C Bancal, B Crestani - Expert Opinion on Drug Safety, 2005 - Taylor & Francis
… these studies [56] suggested that inhaled corticosteroids reduced the decline of lung function.
A … the effect of 6 months discontinuation of inhaled corticosteroids in COPD patients after 4 …

Withdrawal of inhaled corticosteroids in COPD patients: rationale and algorithms

S Avdeev, Z Aisanov, V Arkhipov… - … Journal of Chronic …, 2019 - Taylor & Francis
… Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive
pulmonary disease: the COPE study. Am J Respir Crit Care Med. 2002;166:1358–1363. …

Discontinuation of inhaled corticosteroids from triple therapy in COPD: effects on major outcomes in real world clinical practice

S Suissa, S Dell'Aniello, P Ernst - COPD: Journal of Chronic …, 2022 - Taylor & Francis
… -based guidelines for the withdrawal of inhaled corticosteroids (ICS) in … We assessed the
effect of ICS discontinuation on the … Subjects who discontinued ICS were matched 1:1 on time-…