Low dose inhaled corticosteroids and the prevention of death from asthma

JC Kips, RA Pauwels - Thorax, 2001 - thorax.bmj.com
… the first three months after discontinuation of inhaled corticosteroids was higher than the rate
… of low-dose inhaled corticosteroids is associated with a decreased risk of death from asthma…

Weaning from inhaled corticosteroids in COPD: the evidence

S Suissa, A Rossi - European Respiratory Journal, 2015 - Eur Respiratory Soc
… Finally, the trial should have sufficiently long follow-up to also measure the anticipated benefit
from ICS discontinuation in terms of risk reduction, particularly on pneumonia. Indeed, the …

Pragmatic trial on inhaled corticosteroid withdrawal in patients with COPD in general practice

L van den Bemt, L van den Nieuwenhof… - npj Primary Care …, 2020 - nature.com
… The therapeutic value of inhaled corticosteroids (ICSs) for COPD is limited. … risk when
bronchodilator treatment is optimized. Here we report on the feasibility and risks of ICS withdrawal

[HTML][HTML] Relative efficacy and safety of inhaled corticosteroids in patients with asthma: systematic review and network meta-analysis

B Chipps, B Taylor, V Bayer, A Shaikh… - Annals of Allergy …, 2020 - Elsevier
… or even less likely to result in study discontinuation because of an AE than a moderate-dose …
the risk of an AE leading to study discontinuation (risk ratio, 0.56; 95% CI, 0.14-2.43; vs risk

Effect of inhaled corticosteroid withdrawal on chronic obstructive pulmonary disease exacerbations in patients taking triple therapy at baseline

GT Ferguson, A Shaikh, K Tetzlaff… - … journal of chronic …, 2020 - Taylor & Francis
Purpose In the Withdrawal of Inhaled Steroids during Optimized Bronchodilator Management
(WISDOM) trial, inhaled corticosteroid (ICS) withdrawal in patients with chronic obstructive …

A re-evaluation of the role of inhaled corticosteroids in the management of patients with chronic obstructive pulmonary disease

A D'Urzo, JF Donohue, P Kardos… - Expert opinion on …, 2015 - Taylor & Francis
… Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive
pulmonary disease: the COPE study. Am J Respir Crit Care Med 2002;166:1358-63 …

A framework for step down or therapeutic re-organization for withdrawal of inhaled corticosteroids in selected patients with COPD: a proposal for COPD management

C Micheletto, F Braido, M Contoli… - … Journal of Chronic …, 2019 - Taylor & Francis
… of withdrawal of inhaled corticosteroids in COPD wherein it was reported that withdrawal of
ICS did … relevant risk of severe exacerbation was still present (RR >1.2). Citation38 Moreover, …

How and when to use inhaled corticosteroids in chronic obstructive pulmonary disease?

E Antón - Expert Review of Respiratory Medicine, 2013 - Taylor & Francis
Inhaled corticosteroids (ICSs) are widely used in chronic obstructive pulmonary disease (COPD). …
Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive …

Use of inhaled corticosteroids and risk of fractures

TP Van Staa, HGM Leufkens… - Journal of Bone and …, 2001 - Wiley Online Library
… fracture risk after cessation of inhaled corticosteroids, each user who stopped therapy before
the end of study was followed from 91 days after the last inhaled corticosteroid prescription …

Applying the wisdom of stepping down inhaled corticosteroids in patients with COPD: a proposed algorithm for clinical practice

AG Kaplan - … Journal of Chronic Obstructive Pulmonary Disease, 2015 - Taylor & Francis
… 24% fewer rehospitalizations and a 29% risk reduction for mortality during a 1-year follow-up…
demonstrated that discontinuation of ICS was associated with a 37% reduction in the risk of …