… Additionally, we highlight those CMPs for which further chemical biology efforts are required
to identify suitable enzymatic inhibitors to probe their biology and transfer them into the clinic…

… chemistry have … biological systems; (2) significant contributions of academic research to the
identification and characterization of chemical tools and probes, as well as to drug discovery. …

… interesting areas of drug discovery. In particular, we claim that network biology will play a …
two areas where we believe network and system biology strategies are more likely to have …

… Herein, we discuss the crucial integration of chemical biology knowledge, drug discovery
strategies, and medicinal chemistry to foster structure–mechanism of action studies and …

… biological systems can be viewed as networks of chemical reactions that can be analyzed
mathematically using ODEs. The use of ODEs in biological … in computational systems biology 3…

… chemical space. This contribution introduces key investigations in computational chemical
biology … and future potential to impact drug discovery. Conclusions: Computational methods of …

… in chemical biology and drug discovery. However, discovering the targets of small molecules
is often the most challenging and time-consuming step for chemical biology researchers. …

… chemistry community to share technology, resources, and compounds in the context of “Distributed
Drug Discovery” to find treatments for diseases of the developing nations. (371-373) …

… of Chemical Biology, this book provides a fairly general overview of the role of chemical
biology in drug discovery and development and in understanding biological mechanisms of …

… Bottom-up systems biology … by systems biology and discuss limitations of the top-down and
bottom-up approaches, which, despite these limitations, have already led to the discovery of …