Discrete dynamic modeling of cellular signaling networks
… concepts of discrete dynamic modeling, particularly focusing on Boolean dynamic models.
We … This chapter introduced discrete dynamic modeling and network analysis approaches. …
We … This chapter introduced discrete dynamic modeling and network analysis approaches. …
Discrete dynamic modeling of signal transduction networks
A Saadatpour, R Albert - Computational Modeling of Signaling Networks, 2012 - Springer
… Boolean modeling, the simplest type of discrete dynamic modeling, … to analyze the dynamics
of signaling networks. This is … a Boolean dynamic framework applied to the modeling of the …
of signaling networks. This is … a Boolean dynamic framework applied to the modeling of the …
Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer
… Dynamic models of signaling networks can map the … on discrete dynamic models of cancer
and highlight their predicted therapeutic strategies. We believe dynamic network modeling …
and highlight their predicted therapeutic strategies. We believe dynamic network modeling …
Discrete modeling for integration and analysis of large-scale signaling networks
P Vignet, J Coquet, S Auber, M Boudet… - PLoS Computational …, 2022 - journals.plos.org
… dynamical response of complex networks combining transcriptional regulation processes,
signalling networks and metabolism. Although a wide variety of dynamical modeling …
signalling networks and metabolism. Although a wide variety of dynamical modeling …
Discrete dynamic modeling: a network approach for systems pharmacology
… of signaling pathways, but a paucity of kinetic and temporal information. Discrete dynamic
modeling … We argue that discrete dynamic models can be used to facilitate many of the goals of …
modeling … We argue that discrete dynamic models can be used to facilitate many of the goals of …
Discrete logic modeling of cell signaling pathways
… network models are a meaningful tool to study large network … By introducing a model
describing pathways involved in … to model cell signaling pathways with Boolean network models. …
describing pathways involved in … to model cell signaling pathways with Boolean network models. …
Modeling approaches for qualitative and semi-quantitative analysis of cellular signaling networks
R Samaga, S Klamt - Cell communication and signaling, 2013 - Springer
… models enable to derive qualitative properties of the system’s dynamics by means of discrete
dynamic modeling [… at gaining insights into the qualitative dynamic properties of the system, …
dynamic modeling [… at gaining insights into the qualitative dynamic properties of the system, …
A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach
… Considering the complexity of this insulin-PKR signaling network, we applied modeling to …
Here we applied a novel discrete dynamic modeling approach using three-state logic variables…
Here we applied a novel discrete dynamic modeling approach using three-state logic variables…
Discrete dynamic modeling with asynchronous update, or how to model complex systems in the absence of quantitative information
SM Assmann, R Albert - Plant systems biology, 2009 - Springer
… Here we describe a method by which cellular signaling networks can be assembled … network
analysis and discrete dynamic modeling primarily in the context of cell signaling pathways. …
analysis and discrete dynamic modeling primarily in the context of cell signaling pathways. …
Dynamic simulation of regulatory networks using SQUAD
… for the dynamic simulation of signaling networks using the standardized qualitative dynamical
systems approach. SQUAD converts the network into a discrete dynamical system, and it …
systems approach. SQUAD converts the network into a discrete dynamical system, and it …
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