… sensitivity to change in COPD and to treatment … deterioration. We used data collected as
part of the Inhaled Steroids in Obstructive Lung Disease (ISOLDE) study of fluticasone in COPD. …

… management of COPD, a disease in which deterioration may … deterioration (CID) endpoint
to measure short-term disease … of the CID endpoint in measuring disease activity in COPD. …

… for COPD has been shown to modify disease progression. … of this disease, the progression
of patient reported outcomes over … overall deterioration in COPD from the viewpoint of patients …

… 172 patients with COPD referred to the rehabilitation program, 92 experienced deterioration
in … We excluded 13 patients with overt cardiac disease who met at least one of the following …

… Exacerbations of chronic obstuctive pulmonary disease (COPD) are associated with … patients
whereas the current study included only the 613 patients for whom a rate of deterioration in …

… COPD as their discontinuation leads to disease deterioration… in patients with COPD results
in persistent deterioration in … of COPD, as their discontinuation leads to deterioration even …

… relies on it as an indicator of disease progression, categorize COPD patients on the basis of
… on rapid deterioration of lung function in COPD patients. current smoking, disease severity, …

… Exacerbations of COPD are frequently associated with deterioration in gas exchange and
associated hypoxemia. Unsurprisingly, increased inequality in V/Q relationships appears to be …

… the onset of the disease to the level of … of deterioration varied widely among individual
patients, but we suggest that the rate for each patient with chronic obstructive pulmonary disease …

… property of a change in CAT score from a stable baseline visit for detecting acute
deterioration in health status visits of chronic obstructive pulmonary disease (COPD) patients. …