… We found that the microsatellite attributes copy number, repeat motif and type of mutation …
-read and short-read NGS platforms can be used to sequence short tandem repeats accurately, …

… in signal transduction between FLT3/KD and FLT3/ITD mutations may help explain the
distinctive disease progression and prognosis in leukemias harboring these mutations. …

… a pivotal role in multiple genetic diseases, population genetics applications, and forensic
casework. STRs exhibit rapid mutation rates of ∼10 −5 mutations per locus per generation, …

… More recently, allele length mutations which increase the number of tandemly … of mutation
due to unstable trinucleotide repeats in meioses not associated with pathogenesis of disease …

… Forensic DNA profiling utilizes autosomal short tandem … directly causing or predicting
disease. Such a demonstration … causative or predictive of disease. Regardless, the likelihood of …

… repeats and the mutation rate was observed. Our data demonstrate that mutation rates of …
orders of magnitude and that different alleles at one locus exhibit different mutation rates. …

… that are depleted of mutations has proven a useful strategy for interpreting the significance
of de novo variation in developmental disorders 1 , prioritizing rare disease variants 2 , and …

… focused on somatic variation at a small number of disease-associated loci, we report a novel
… in disease, common mutations affecting Msh3 may contribute to biases in mutation patterns …

… the pathways that lead from mutation to disease. This review will address … mutation process
and elaborate on the pathogenic pathways that lead from expanded repeats to the diseases …

… disease, 8 ,9 and in PGRN null mutation carriers, parkinsonism has already been reported.
On the other hand, dementia is common in patients with Parkinson disease (PD… Short tandem …