… Short tandem repeats (STRs) are short DNA fragments with a length of 2–6 nucleotides that
are consecutively replicated at certain areas of DNA. Expansions of short tandem … mutations …

… with great care, as from our data the mutation profiles of the different markers varies widely.
… originated from screening clinics for inherited disease where ethnic information had been …

… Short tandem repeats (STRs) are found in many prokaryotic and eukaryotic genomes, and
… be associated with human diseases [13]. A preeminent example is the Huntington disease, a …

… Many of these loci are functional short tandem repeats (STRs) … These type of loci share
the mutation dynamics of the rest of … This group of genetic diseases has not been detected in …

… Activating mutations in FLT3 have been identified in approximately 30% of patients with …
mutations observed in this disease. Frequently, the mutation is an in-frame internal tandem …

… The assumed ancestral haplotype, presumed to carry the disease mutation, was then … -Castle
law to short tandem repeats from HLA II favors the locus D6S291 for disease susceptibility, …

… diseases such as Huntington disease. Apart from their role in … sequence repeats (SSRs), or
short tandem repeats (STRs), and … Most mutations in TRs are due not to point mutations but …

… , at a ratio of 6.04:1, and the mutation rate tended to increase … mutations for long alleles
and expansion mutations for short alleles. No obvious bias was observed in the overall mutation …

… Background: Duchenne and Becker muscular dystrophies (DMD/BMD) are X-linked diseases
caused by mutations in the dystrophin gene at Xp21.2; they include gross deletions (60%), …

… event in these diseases; however, sequence contractions, deletions, and mutations have
also … Chromatin domain boundaries were recently reported to co-localize with short tandem …