[HTML][HTML] Unbiased proteomic approach identifies unique and coincidental plasma biomarkers in repetitive mTBI and AD pathogenesis
… A limitation of this study and other plasma proteomic studies is the efficient and comprehensive
depletion of abundant plasma proteins, as it is well-known that their presence in a …
depletion of abundant plasma proteins, as it is well-known that their presence in a …
Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression
IA Szilagyi, CL Vallerga, CG Boer, D Schiphof… - …, 2023 - academic.oup.com
… protein levels and disease severity to examine whether protein biomarkers are linked to
disease activity. Furthermore, we examined disease severity and progression in multiple joints …
disease activity. Furthermore, we examined disease severity and progression in multiple joints …
Genomic atlas of the human plasma proteome
… architecture of the human plasma proteome in healthy blood donors … plasma protein levels,
we apply an integrated approach that links genetic variation with biological pathway, disease, …
we apply an integrated approach that links genetic variation with biological pathway, disease, …
Proteomic and metabolomic approaches in the search for biomarkers in chronic kidney disease
M Cañadas-Garre, K Anderson, J McGoldrick… - … of proteomics, 2019 - Elsevier
… Chronic kidney disease progression, classification according to estimated glomerular filtration
rate and albuminuria, main therapeutic approaches and current available biomarkers. The …
rate and albuminuria, main therapeutic approaches and current available biomarkers. The …
[HTML][HTML] Plasma protein profiling of mild cognitive impairment and Alzheimer's disease using iTRAQ quantitative proteomics
… Methods Isobaric tags (iTRAQ) and proteomic methods were used to identify potential plasma
… Relative protein expression level changes were quantified in plasma of 411 cognitively …
… Relative protein expression level changes were quantified in plasma of 411 cognitively …
Undulating changes in human plasma proteome profiles across the lifespan
… during aging, we developed the DE-SWAN approach. Considering a vector l of k unique
ages, we iteratively used l k as the center of a 20-year window and compared protein levels of …
ages, we iteratively used l k as the center of a 20-year window and compared protein levels of …
[HTML][HTML] Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain
… to diagnose or monitor human disease. However, in neurodegenerative disorders it has so
far been more difficult to use unbiased large-scale proteomic approaches to discover blood-…
far been more difficult to use unbiased large-scale proteomic approaches to discover blood-…
Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma
… For plasma proteomic model development, we used LASSO logistic and ridge regressions,
and the flow chart of biostatistical analysis is shown in Figure 2A. More details about sample …
and the flow chart of biostatistical analysis is shown in Figure 2A. More details about sample …
[HTML][HTML] Deeper insight into chronic kidney disease-related atherosclerosis: comparative proteomic studies of blood plasma using 2DE and mass spectrometry
M Luczak, D Formanowicz, Ł Marczak… - Journal of translational …, 2015 - Springer
… Moreover, the risk of cardiovascular disease (CVD) development in patients … proteomic
analysis of blood plasma from patients in various stages of CKD and thus distinct progression of …
analysis of blood plasma from patients in various stages of CKD and thus distinct progression of …
[HTML][HTML] Plasma proteomics identify biomarkers and pathogenesis of COVID-19
T Shu, W Ning, D Wu, J Xu, Q Han, M Huang, X Zou… - Immunity, 2020 - cell.com
… Here, we profiled host responses to COVID-19 by performing plasma proteomics of a cohort
… numerous COVID-19-associated alterations of plasma proteins. We developed a machine-…
… numerous COVID-19-associated alterations of plasma proteins. We developed a machine-…