Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets

TH Cao, DJL Jones, AA Voors, PA Quinn… - European journal of …, 2020 - Wiley Online Library
… the pathogenesis of disease progression in HF, but might also identify new therapeutic targets.
… about pathogenesis of disease progression and potential novel treatment targets in HF by …

[HTML][HTML] Epigenetic modifications and potential new treatment targets in diabetic retinopathy

L Perrone, C Matrone, LP Singh - Journal of Ophthalmology, 2014 - hindawi.com
… of epigenetics in the progression of DR. Further … new insights into the pathogenesis of DR
and will open the way for the discovery of novel therapeutic targets to prevent DR progression. …

[HTML][HTML] Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment

R Loera-Valencia, J Goikolea… - The Journal of steroid …, 2019 - Elsevier
… evidence indicating their influence in the progression of the disease. This review gives a broad
… cholesterol metabolites as valuable targets for prevention and alternative AD treatments. …

[HTML][HTML] Intracellular galectins in cancer cells: potential new targets for therapy

MC Vladoiu, M Labrie… - … journal of oncology, 2014 - spandidos-publications.com
… and metastasis, they also represent attractive targets for cancer therapy. This has been
well-… these proteins can also alter tumor progression through their interaction with intracellular …

Endocan or endothelial cell specific molecule-1 (ESM-1): a potential novel endothelial cell marker and a new target for cancer therapy

S Sarrazin, E Adam, M Lyon, F Depontieu… - … et Biophysica Acta (BBA …, 2006 - Elsevier
… We will then focus on the involvement of endocan in tumor progression, with its major role
described so far of being a co-receptor for HGF/SF, a well-known angiogenic growth factor [9]. …

The network of epithelial–mesenchymal transition: potential new targets for tumor resistance

D Nantajit, D Lin, JJ Li - Journal of cancer research and clinical oncology, 2015 - Springer
… In this review, we highlight the potential key therapeutic targets of EMT linked with tumor
aggressiveness, hypoxia, angiogenesis and cancer stem cells, emphasizing on an emerging …

Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy

K Izuishi, K Kato, T Ogura, T Kinoshita, H Esumi - Cancer research, 2000 - AACR
… extreme deficiency of oxygen and nutrients, tolerance might serve as a new target for
anticancer drugs. In the present study, we identified two possible candidate drugs for this purpose. …

Potential new targets in arthritis therapy: interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis

MI Koenders, WB Van Den Berg - Annals of the rheumatic diseases, 2006 - ard.bmj.com
… To speculate on the potential of IL-17 as a therapeutic target in the treatment of RA, we should
position this T cell cytokine in the network and cascades of proinflammatory cytokines that …

CKD-MBD: from the pathogenesis to the identification and development of potential novel therapeutic targets

RM Elias, MA Dalboni, ACE Coelho… - Current Osteoporosis …, 2018 - Springer
… From the uncertainty of the pathophysiology to the disappointing results with a classic
treatment approach, a complete revision is necessary. New treatments and particularly new

c-Met is a potentially new therapeutic target for treatment of human melanoma

N Puri, S Ahmed, V Janamanchi, M Tretiakova… - Clinical cancer …, 2007 - AACR
Purpose: c-Met is a receptor tyrosine kinase involved in cell growth, invasion, metastases, and
angiogenesis. In this study, we investigated the role of c-Met in melanoma biology using a …