Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance

SM Raefsky, MP Mattson - Free Radical Biology and Medicine, 2017 - Elsevier
… Such general age-related alterations in neuronal mitochondria are … disease-specific
mechanisms of neuronal dysfunction and death, both upstream and downstream of mitochondrial

Mitochondria, energy, and metabolism in neuronal health and disease

D Trigo, C Avelar, M Fernandes, J Sá… - FEBS …, 2022 - Wiley Online Library
… Detailed knowledge of the coupling between mitochondrial … of mitochondrial and neuronal
function in health and disease. The plasticity and transient characteristics of the mitochondrial

Mitochondria at the neuronal presynapse in health and disease

MJ Devine, JT Kittler - Nature Reviews Neuroscience, 2018 - nature.com
Mitochondria are also increasingly … mitochondria in maintaining neuronal homeostasis and
how dysfunctional presynaptic mitochondria might contribute to the development of disease. …

[HTML][HTML] Nitric oxide, mitochondria and neurological disease

SJR Heales, JP Bolaños, VC Stewart… - … et Biophysica Acta (BBA …, 1999 - Elsevier
Neuronal mitochondrial damage as a result of astrocyte generation of NO and ONOO − . …
Since NOS-positive neurones actually appear to be resistant to glutamate receptor activation, it …

Mitochondria and neuronal survival

DG Nicholls, SL Budd - Physiological reviews, 2000 - journals.physiology.org
… of mitochondria in situ within neurons under physiological and pathophysiological conditions.
Here we review the functional bioenergetics of isolated mitochondria, … to intact neurons. …

Roles of mitochondria in health and disease

MR Duchen - Diabetes, 2004 - Am Diabetes Assoc
… opener diazoxide increases mitochondrial resistance to oxidative injury… neurons, the
neurotoxicity of glutamate depends on mitochondrial calcium uptake, but the toxicity to mitochondria

The role of mitochondria in neurodegenerative diseases: the lesson from Alzheimer's disease and Parkinson's disease

G Monzio Compagnoni, A Di Fonzo, S Corti… - Molecular …, 2020 - Springer
… The purpose of the present review is to highlight the importance of mitochondria in … most
common neurodegenerative diseases: Alzheimer’s disease (AD) and Parkinson’s disease (PD). …

Mitochondrial dysfunction in diseases, longevity, and treatment resistance: tuning mitochondria function as a therapeutic strategy

K Tomita, Y Kuwahara, K Igarashi, MH Roudkenar… - Genes, 2021 - mdpi.com
mitochondrial transplantation (mtTP) for treatment-resistant … involvement of mitochondria
in normal and disease conditions, … (treatment resistance). We also describe the crucial role of …

Mitochondria and neuronal activity

O Kann, R Kovács - American Journal of Physiology-Cell …, 2007 - journals.physiology.org
… tool to study mitochondrial function during neuronal activity, with … on mitochondrial Ca 2+
transport, mitochondrial membrane potential (ΔΨ m ), and energy metabolism during neuronal

Mitochondrial diseases of the brain

RK Chaturvedi, MF Beal - Free Radical Biology and Medicine, 2013 - Elsevier
… DNA mutations, gene mutations, altered mitochondrial dynamics (mitochondrial fusion/…
proteins with mitochondria in these diseases. We highlight the therapeutic role of mitochondrial