What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?

DA Gallagher, AJ Lees, A Schrag - Movement Disorders, 2010 - Wiley Online Library
Nonmotor symptoms (NMS) are increasingly recognized as important and neglected aspects
of Parkinson's disease (PD). We evaluated their relative frequency and comparative impact …

A collaborative study on the malignant syndrome in Parkinson's disease and related disorders

H Takubo, T Harada, T Hashimoto, Y Inaba… - … & Related Disorders, 2003 - Elsevier
… A total of 99 episodes were encountered in 93 patients (72 with Parkinson's disease and
21 with secondary parkinsonism); one patient had four recurrences of MS and three patients

Identifying prodromal Parkinson's disease: pre‐motor disorders in Parkinson's disease

RB Postuma, D Aarsland, P Barone… - … Disorders, 2012 - Wiley Online Library
Increasing recognition that Parkinson's disease (PD) may start outside of the substantia nigra
has led to a rapidly expanding effort to define prodromal stages of PD, before motor signs …

High frequency of sleep disorders in Parkinson's disease and its relationship with quality of life

MA Sobreira-Neto, MA Pena-Pereira… - European …, 2017 - karger.com
… major sleep disorders in patients with Parkinson’s disease (… disorders, and assess the
relationship of those disorders with … was performed involving 88 consecutive patients with PD from …

[图书][B] Psychiatric and cognitive disorders in Parkinson's disease

SE Starkstein, M Merello - 2002 - books.google.com
… Emotional and cognitive disorders are common in Parkinson's disease, but are … of Parkinson's
disease, based on the neurologic and psychiatric assessment of hundreds of patients by …

Mood disorders in Parkinson's disease

LCS Tan - Parkinsonism & related disorders, 2012 - Elsevier
… Of the behavioural disorders in PD, mood disorders are amongst the most common and can
… Prevalence of anxiety disorders and anxiety subtypes in patients with Parkinson’s disease. …

Cognitive disorders in Parkinson's disease: confirmation of a spectrum of severity

K Dujardin, AJH Moonen, H Behal, L Defebvre… - … & related disorders, 2015 - Elsevier
Introduction Clinical presentation and progression of cognitive disorders in Parkinson's
disease (PD) is heterogeneous. Our objective was to confirm prospectively a previous …

Sleep disorders in Parkinson's disease: many causes, few therapeutic options

NJ Diederich, DJ McIntyre - Journal of the neurological sciences, 2012 - Elsevier
… James Parkinson noted disorders of sleep in the late stages of Parkinson's disease (PD)
in … Nonetheless, PD has been predominantly considered a motor disorder consisting of the …

Sleep disorders and the natural history of Parkinson's disease: the contribution of epidemiological studies

S Zoccolella, M Savarese, P Lamberti, R Manni… - Sleep medicine …, 2011 - Elsevier
… Sleep disorders (SD) are one of the most frequent non-motor manifestations of
Parkinson's disease (PD). Recent studies showed that SD may precede the onset of PD. …

Parkinson's disease and anxiety

K Walsh, G Bennett - Postgraduate medical journal, 2001 - academic.oup.com
… 37 A number of studies have examined anxiety in patients Parkinson’s disease with on-off
symptoms; these have found that patients have more anxiety in the off state than in the on state…