Disruption of gap junctions in toxicity and carcinogenicity

JK Chipman, A Mally, GO Edwards - Toxicological Sciences, 2003 - academic.oup.com
Although the specific role of connexin-mediated gap junctional intercellular communication
in the control of cell homeostasis, proliferation, and death are still not clear, several lines of …

Immunoglobulin and cytokine expression in mixed lymphocyte cultures is reduced by disruption of gap junction intercellular communication

E OVIEDO‐ORTA, P Gasque… - The FASEB …, 2001 - Wiley Online Library
… connexins and functional gap junctions in lymphocytes is highly suggestive that they play a
physiological role. We now show that disruption of gap junctional communication influences …

[HTML][HTML] Diabetes-induced disruption of gap junction pathways within the retinal microvasculature

H Oku, T Kodama, K Sakagami… - … ophthalmology & visual …, 2001 - iovs.arvojournals.org
gap junctions within the retinal microvasculature, the spread of this tracer was dramatically
reduced by DSA (30 μM, 16-doxyl-stearic acid), which is a gap junction … via gap junctions from …

Disruption of gap junctional communication within the ovarian follicle induces oocyte maturation

S Sela-Abramovich, I Edry, D Galiani, N Nevo… - …, 2006 - academic.oup.com
… of gap junctional communication (GJC) within the ovarian follicle. In the present study, we
examined the hypothesis that disruption … ), a known blocker of gap junctions. We found that this …

Selective disruption of gap junctional communication interferes with a patterning process in hydra

SE Fraser, CR Green, HR Bode, NB Gilula - Science, 1987 - science.org
… molecules through the gap junctions and the rate of return of gap junction coupling after …
the major rat liver gap junction protein (27,000 daltons) recognize a gap junction antigen in …

[HTML][HTML] Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells

F Kouzi, K Zibara, J Bourgeais, F Picou, N Gallay… - Oncogene, 2020 - nature.com
… reported the effects of gap junction disruption between murine … us to show that disruption
of gap junctions by CBX reduced … The involvement of gap junction disruption in our models is …

Disruption of gap junctions reduces biomarkers of decidualization and angiogenesis and increases inflammatory mediators in human endometrial stromal cell cultures

J Yu, J Wu, IC Bagchi, MK Bagchi, N Sidell… - Molecular and cellular …, 2011 - Elsevier
… and functional gap junctions between decidualized ESC increase concomitantly with
morphological differentiation following E/P/c treatment. Disruption of gap junctions using …

Involvement of meiotic resumption in the disruption of gap junctions between cumulus cells attached to pig oocytes

N Isobe, T Maeda, T Terada - Reproduction, 1998 - rep.bioscientifica.com
… showing that the disruption does not trigger meiotic … exhibiting loss of gap junctions within
all cumulus cell layers … is induced by the disruption of gap junctions within cumulus cells, …

Disruption of gap junctional intercellular communication by lindane is associated with aberrant localization of connexin43 and zonula occludens-1 in 42GPA9 Sertoli …

N Defamie, B Mograbi, C Roger, L Cronier… - …, 2001 - academic.oup.com
… , including gap junction intercellular communication. Using the 42GPA9 Sertoli cell line,
we show that lindane, at a non-cytotoxic dose (50 μM), abolished gap junction intercellular …

Gap junctions

DA Goodenough, DL Paul - Cold Spring Harbor …, 2009 - cshperspectives.cshlp.org
Gap-junctional channels are composed of hexamers of medium-… of gap junctions have been
explored by studying mutations in flies, worms, and humans, and targeted gene disruption in …