… and more specifically amorphous solid dispersions are certainly a valuable formulation
strategy to enhance the solubility and dissolution rate of a poorly soluble API. One striking …

… challenge to formulation scientists, as dissolution rate is the rate-limiting … formulation and
formulation strategies are employed to enhance the aqueous solubility and/or dissolution rate…

… is said to be dissolution rate limited. Developing an effective formulation for these drugs has
… substrate has been considered as a possible formulation strategy to overcome this problem. …

… Different formulation strategies have been proposed for … It exhibited a much higher in vitro
dissolution profile than both the … Whitney equation, the dissolution rate is linearly proportional …

… can significantly enhance the dissolution rate. In another study… reported formulations
dramatically higher dissolution rates … in unstable formulations with lower dissolution rates. PVPs …

… Therefore, pharmaceutical formulations scientists need to … Expert opinion: The diversity of
poorly soluble APIs formulated … rational approach to decide the correct formulation is needed. …

… , which ultimately leads to better saturation solubility and dissolution rate. Among solid
dispersions, glass solutions are currently applied the most and differ from solid solutions in the …

… dissolution rate or low bioavailability. Hence to overcome such problems various techniques
have been introduced to enhance the dissolution rate … is to enhance the dissolution rate of …

… Formulation strategies aimed at improving dissolution of these compounds are often guided
… their intrinsic dissolution rates (IDR, μg/min/cm 2 ), ie, the surface specific dissolution rate of …

… as the drug dissolution rate is a dynamic property that relates more closely to the bioavailability
rate. It is important to improve the solubility and/or dissolution rate for poorly soluble …