过去一年中添加的文章,按日期排序

[HTML][HTML] Powder Self-Emulsifying Drug Delivery System for Mitotane: In Vitro and In Vivo Evaluation

M Skiba, V Lefébure, F Bounoure, N Milon, M Thomas… - Pharmaceutics, 2024 - mdpi.com
2 天前 - … , as they may increase drug solubility, dissolution velocity, and … by its extremely
poor aqueous solubility. This research … for ameliorating the solubility, dissolution rate, and oral …

Nanocrystallization strategies for enhanced HIV drug performance from solubility to sustained action

J Babaei, F Hosseini, A Shadab, A Amouei, R Babaei - Discover Medicine, 2024 - Springer
3 天前 - solubility and dissolution rates by reducing drug particles to the nanometer scale.
This increased surface area improves drug solubility and … by the poor water solubility of many …

Nanocrystal Agglomerates of Curcumin Prepared by Electrospray Drying as an Excipient‐Free Dry Powder for Inhalation

S Emami, Z Hemmati, S Yaqoubi… - Advances in …, 2024 - Wiley Online Library
7 天前 - … solution, low water solubility, poor oral bioavailability, … solubility and dissolution
rate, enhanced mucoadhesion, and enhanced membrane permeability [67]. The dissolution rate

Effect of Co‐Crystallization on Physicochemical and Pharmacokinetic Properties of Rifaximin

DC Sakhiya, CH Borkhataria - ChemistrySelect, 2024 - Wiley Online Library
7 天前 - … properties like saturation solubility, dissolution rate, flow-ability… poor solubility as
it is a brick dust candidate (BCS class IV). Being a BCS class IV drug, it possesses the solubility

[PDF][PDF] Solubility of chlordiazepoxide in supercritical carbon dioxide: modeling investigation

NS ARDESTANI, SA SAJADIAN… - … European Meeting on …, 2024 - epubl.ktu.edu
10 天前 - … group, has a poor aqueous solubility and dissolution rate in water. … The solubility
of medicines in SCF is also critical for the … of precise solubility data in scCO₂ is imperative. …

Co-amorphous systems of sulfasalazine with matrine-type alkaloids: Enhanced solubility behaviors and synergistic therapeutic potential

X Chen, Y Qin, L Wang, Y Zhu, H Zhang, W Liu… - European Journal of …, 2024 - Elsevier
13 天前 - … clinically, possesses poor solubility, resulting in … dissolution rates compared to
crystalline SULF. The underlying mechanisms for the increased solubility and dissolution rates in …

[HTML][HTML] Drug Loading Methods and Kinetic Release Models Using of Mesoporous Silica Nanoparticles as a Drug Delivery System: A Review

AH Khalbas, TM Albayati, NS Ali, IK Salih - South African Journal of …, 2024 - Elsevier
13 天前 - … market exhibit poor water solubility, which adversely affects the dissolution rate of
drugs … stable amorphous drugs with improved dissolution rates, solubility, and bioavailability. …

Innovations in Oral Dispersible Tablets: Improving Bioavailability and Patient Compliance in NSAID Therapies

P Karanje - International Journal of Medical Toxicology and Legal …, 2024 - ijmtlm.org
16 天前 - … have significantly enhanced drug dissolution rates, taste-… by challenges such as
poor solubility, variable bioavailability … These include enhancing dissolution rates to ensure …

[HTML][HTML] Production of Biopolymeric Microparticles to Improve Cannabigerol Bioavailability

L Baldino, S Sarnelli, M Scognamiglio, E Reverchon - Materials, 2024 - mdpi.com
17 天前 - … limited by its poor water solubility and low dissolution rate. To … Dissolution tests
were used to verify that a reduction of CBG particle size significantly increased its dissolution rate

[HTML][HTML] Rheology, Stability, and Physicochemical Properties of NaOH-Tannic Acid Solvent for β-Chitin Dissolution

ST Wang, PJ Huang, SK Chen, CR Shen, YP Chen… - Food …, 2024 - Elsevier
21 天前 - … The applicability of chitin in food systems is limited by its poor solubility in ordinary
… a repeated freeze-thaw process for dissolving chitin. The highest chitin solubility in 8% NaOH/…