… solubility and dissolution rates. They require enhancement in solubility and dissolution rate
… The poor solubility of new chemical entities decreases the oral bioavailability of these drugs …

… The equation describes the relationship between dissolution rate and solubility. It also
reflects the effect of dissolution pH on the dissolution rate of a drug with pH-dependent solubility. …

… From now on the solubility or dissolution of the dose ranges in the various biophysiological
media to which the drug substance or formulated drug substance will be exposed is expected …

… solubility, dissolution and bioavailability of drugs with poor … solubility, drug permeability,
dissolution rate, first-pass metabolism and susceptibility to efflux mechanisms, aqueous solubility …

… Slight dissolution rates related to poor water-solubility are one of the well-known difficulties
… , shows a poor dissolution rate. This study is intended to enhance the drug dissolution rate by …

… The drug with poor water solubility cause slow dissolution rates generally shows erratic and
incomplete absorption leading to low bioavailability when administered orally. In the present …

… rates of these bacteria and the rates of dissolution of phenanthrene suggest that the dissolution
rate of the hydrocarbon may limit the rate of … added carbon sourcewas poor and probably …

… This study focuses on improving the dissolution rate of extremely hydrophobic quercetin (3, …
is shown to be poor and its pharmacological effect is restricted by its poor solubility and fast …

… The dissolution rate and the release rate of a drug are essential to know for drug characterization.
Poor aqueous solubility is likely to give rise to increased formulation difficulties during …

… A selected model drug under study has poor water solubility and therefore limited oral …
based on physical stability, improved solubility and dissolution rates, ease of manufacturing, and …