… dissolved in the gastric fluid1. However, a poorly water soluble drug with poor solubility and
low dissolution rate … Solubility of such drugs can be improved by incorporating the drug in a …

… The poor solubility of drug substances in water and their low dissolution rate in aqueous GIT
fluid often leads … Since only dissolved drug can pass the gastro intestinal membrane, proper …

… solubility, and most drugs should be lipophilic to permeate the biological membranes via
passive diffusion. The poor solubility and low dissolution rate of … with dissolution ratelimited low …

… The poor solubility and low dissolution rate of poorly water … by increasing the solubility
and dissolution rate of the drug in … site due to slow dissolution rate and perhaps leading to …

… FeSSIF is a poorer means of determining intestinal saturation solubility in the fed state. …
verified in the present study suggests that dissolution rate should not be estimated from solubility …

… with poor aqueous solubility. Hence various techniques are used for the improvement of the
solubility … The advantages offered by nanosuspension is increased dissolution rate is due to …

… Moreover, the poor solubility and dissolution rate of DMP at elevated pH values limit the
ability for its delivery via rectal or buccal routes and necessitate the use of powerful …

… INDO is rapidly absorbed after oral administration but since it has poor aqueous solubility
its dissolution rate is very low5. In this research work, we used solvent evaporation method to …

… Thus the combination of its poor solubility and high dose constitutes a severe limitation to its
… would increase the total solubility and therefore the dissolution rate of weakly acidic drugs …

… CoQ 10 ) with high aqueous solubility and dissolution rate. Among various carriers screened…
enhanced the solubility of CoQ 10 to the greatest extent. However, it exhibited poor stability …