Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy

G Virella, RE Carter, A Saad, EG Crosswell… - Clinical …, 2008 - Elsevier
oxidized LDL (oxLDL) are mostly of the pro-inflammatory IgG 1 and IgG 3 isotypes. We
measured IgG and IgM oxLDL … IgG antibodies predominated over IgM antibodies by an 8:1 ratio. …

Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events

S Tsimikas, ES Brilakis, RJ Lennon, ER Miller… - Journal of lipid …, 2007 - ASBMB
… to oxidized low density lipoprotein (OxLDL) and coronary artery disease (CAD) remains
controversial. IgM and IgG OxLDL … Those with skewed distributions are summarized as medians …

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results …

A Ravandi, SM Boekholdt, Z Mallat, PJ Talmud… - Journal of lipid …, 2011 - ASBMB
… This epidemiological cohort of initially healthy subjects shows that IgG and IgM AA and IC
are … IgM autoantibodies to malondialdehyde-modified LDL (MDA-LDL) as initially described ( …

Natural IgM antibodies against oxidation-specific epitopes

CJ Binder - Journal of clinical immunology, 2010 - Springer
… from detailed studies of the pathogenic role of oxidized LDL (OxLDL), which is generated
and … -prone sn-2 polyunsaturated fatty acid, undergoes oxidation, highly reactive breakdown

Naturally occurring IgM antibodies to oxidation-specific epitopes

CJ Binder - Naturally Occurring Antibodies (NAbs), 2012 - Springer
… later demonstrated that breakdown products that are formed during the oxidation of … For
instance, we could show a significant correlation between IgM antibodies to Cu2+-oxidized LDL

Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis

J Karvonen, M Päivänsalo, YA Kesäniemi… - Circulation, 2003 - Am Heart Assoc
… -oxidized LDL and malondialdehyde-modified LDL (MDA-LDL) and … of IgM, IgG, and IgG2
autoantibodies binding to MDA-LDL … During oxidation, a variety of highly reactive breakdown

Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study

J Su, X Hua, M Vikström, K Leander, B Gigante… - BMC Cardiovascular …, 2013 - Springer
distributed parameters and medians (ranges) or proportions for parameters which were
not normally distributed … of oxidized low density lipoprotein. J Clin Investig. 1996, 98: 815-825. …

Cross‐Reactivity of IgM and IgG Anticardiolipin Antibodies with Oxidized‐Low Density Lipoproteins

J Damoiseaux, AD Jeyasekharan… - Annals of the New …, 2005 - Wiley Online Library
… Native LDL and oxidized LDL were diluted in PBS to 100 μg LDL/mL, and 100 μL per well
(… Because values for aCLAs and anti-oxLDL antibodies had a non-Gaussian distribution, all …

High plasma immunoglobulin (Ig) A and low IgG antibody titers to oxidized low-density lipoprotein are associated with markers of glucose metabolism

M Sämpi, M Veneskoski, O Ukkola… - The Journal of …, 2010 - academic.oup.com
… of other immunoglobulin classes of antibodies, especially IgA binding to oxidized LDL,
however, … Log-transformed values were used to normalize skewed distributions. P < 0.05 was …

Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus

MF Lopes-Virella, G Virella, TJ Orchard, S Koskinen… - Clinical …, 1999 - Elsevier
… , moderate specificity, and distribution among the three major immunoglobulin isotypes,
with … , JL, Increased titer of immunoglobulin A antibody to oxidized LDL in diabetic patients. …