… In summary, a novel 15-spiro diterpenoid dimer bisandrographolide G (1) was isolated from
A. paniculata, and it displayed significantly inhibitory activity against human CES 2 with an …

… have been identified in human body, namely carboxylesterase 1 (CES 1) and carboxylesterase
2 (CES 2) [2]. As one of the most abundant enzymes distributed in human liver, CES 1 …

… 1,2-dione containing diterpenoids using a unified approach, … SAR with the two human
carboxylesterase isoforms. As a … Additionally, LCMS data strongly suggested that dimerization …

… indole diterpenoids that displayed antimicrobial activity and agonistic effect against human
… were assayed for their inhibitory activities against human carboxylesterase 2 (hCE 2). …

… The clerodane diterpene casearin X (1), isolated from the leaves of Casearia sylvestris, is a
… using Caco-2 cells with and without active carboxylesterases (CES). An LC-MS method was …

… Similarly, bile-salt-stimulated lipase and carboxylesterase from human pancreas do not …
Forskolin (XXXI), a diterpene isolated from the roots of Coleus forskohlii [337], is an activator of …

… A series of abietane diterpenoids (tanshinones) was identified and demonstrated to be
potent human CE inhibitors (80). Furthermore, the tanshinones are present in high quantities in …

… In conclusion, three ent-abietane-type diterpenoid dimers proposed to originate from
Diels–Alder cycloaddition were isolated and identified from traditional Chinese medicine E. …

… typical carboxylesterases are essential for the catalytic process of TgTCEA enzyme. To our
knowledge, TgTCEA is the first identified member of the lactone-forming carboxylesterases, …

… called chitobiases, which catalyze decomposition of dimeric GlcNAc units (chitobiose) into
… diterpene, however, the substituents differ considerably when compared to the diterpene …